This product is an anti-idiotypic antibody mimicking disialoganglioside GD2. This antibody can be used for eliciting an immune response in an individual.
Figure 1. The protein structure of ganglidiomab was analyzed by Western blot following SDS–PAGE under non-reducing conditions.
Lode, H. N., Schmidt, M., Seidel, D., Huebener, N., Brackrock, D., Bleeke, M., ... & Siebert, N. (2013). Vaccination with anti-idiotype antibody ganglidiomab mediates a GD 2-specific anti-neuroblastoma immune response. Cancer Immunology, Immunotherapy, 62(6), 999-1010.
Figure 2. Binding of anti-GD2 antibody ch14.18/CHO to both nominal antigen GD2 and ganglidiomab was analyzed with ELISA and compared to negative controls.
Siebert, N., Seidel, D., Eger, C., Brackrock, D., Reker, D., Schmidt, M., & Lode, H. N. (2013). Validated detection of anti-GD2 antibody ch14. 18/CHO in serum of neuroblastoma patients using anti-idiotype antibody ganglidiomab. Journal of immunological methods, 398, 51-59.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0644-WJ-F(E) | Recombinant Mouse Anti-Id (Idiotype) Antibody Fab Fragment (Ganglidiomab) | ELISA | Mouse Fab |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# HPAB-0644-WJ, RRID: AB_3111405)
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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