Recombinant Llama Anti-IL16 Single Domain Antibody (HPAB-N0308-YC-VHH) (CAT#: HPAB-N0308-YC-VHH)
CD16 sdAb was derived from a published llama sdAb (GeneBank sequence EF561291). The CD16 sdAb was spliced to CD19 to test the ability of this CD16 engager to drive NK cell killing. The CD16 sdAb showed cytolytic NK activity similar to rituximab-mediated killing in a chromium release assay with CD19+Raji targets.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to nuclear speckles & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18467/1961_C5_1_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to nuclear speckles & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18467/1961_C5_1_selected.jpg
Figure 2 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48861/1770_D10_3_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48861/1770_D10_3_selected.jpg
Figure 3 Tonsil
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18467/50106_A_4_8.jpg
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18467/50106_A_4_8.jpg
Figure 4 Lymph node
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18467/50106_A_7_8.jpg
(Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18467/50106_A_7_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (Daudi, HEL, HMC-1, RPMI-8226, U-266/70, U-698, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172349-IL16
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172349-IL16
Specifications
- Host Species
- Llama
- Type
- Llama VHH
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- HPAB-N0308-YC-VHH
- Applications
- Function Assay
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2138z | Mouse Anti-IL16 Recombinant Antibody (clone 27G12) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
| ZG-0495J | Mouse Anti-IL16 Recombinant Antibody (ZG-0495J) | WB, ELISA | Mouse IgG |
| VS3-XY855 | Mouse Anti-IL16 Recombinant Antibody (clone 5D8) | ELISA, WB | Mouse IgG1 |
| VS3-WK1718 | Recombinant Rabbit Anti-IL16 Capture Antibody (clone R04-6D1) | ELISA | Rabbit IgG |
| VS3-WK1719 | Recombinant Rabbit Anti-IL16 Detection Antibody (clone R08-8E1) | ELISA | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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