AbPlus™ Anti-IRF5 Magnetic Beads (CBACN-323) (CAT#: VS-0424-XY157)
The AbPlus Anti-IRF5 Magnetic Beads (CBACN-323) is an innovative affinity resin which is bound with anti-IRF5 specific antibody (CBACN-323). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of IRF5 protein under native and denaturing conditions.
Specific Inquiry
Normal Tissue
RNA Expression

Figure 1 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76024/169201_B_9_4_selected.jpg
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76024/169201_B_9_4_selected.jpg

Figure 2 Cerebral cortex
(Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_B_8_5.jpg
(Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_B_8_5.jpg

Figure 3 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_A_6_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_A_6_6.jpg

Figure 4 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_A_9_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_A_9_8.jpg

Figure 5 High expression in spleen
(Cells in red pulp Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in white pulp Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_B_8_4.jpg
(Cells in red pulp Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in white pulp Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_B_8_4.jpg

Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, RPMI-8226, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128604-IRF5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128604-IRF5
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-IRF5 specific antibody (CBACN-323)
- Target
- IRF5
- Immunogen
- N terminus of human IRF5
- Target Species
- Human, Mouse, Rat
- Antibody Clone
- CBACN-323
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.
- Alternative Names
- Interferon Regulatory Factor 5
- Gene ID
- 3663
- UniProt ID
- Q13568
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IRF5"
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Please select product type
IgG Antibody Products
Rabbit Monoclonal Antibody Products
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-3770z | Mouse Anti-IRF5 Recombinant Antibody (clone 34D10) | WB, ELISA, IHC, IP | Mouse IgG1 |
MRO-0870-CN | Recombinant Rabbit Anti-IRF5 Monoclonal Antibody (CBACN-322) | WB, IHC, FC | Rabbit IgG |
MRO-0871-CN | Recombinant Rabbit Anti-IRF5 Monoclonal Antibody (CBACN-323) | WB, IF, IHC, IP, FC | Rabbit IgG |
VS3-WK947 | Rabbit Anti-IRF5 Recombinant Antibody (VS3-WK947) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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