AbPlus™ Anti-IRF5 Magnetic Beads (CBACN-323) (CAT#: VS-0424-XY157)
The AbPlus Anti-IRF5 Magnetic Beads (CBACN-323) is an innovative affinity resin which is bound with anti-IRF5 specific antibody (CBACN-323). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of IRF5 protein under native and denaturing conditions.
Specific Inquiry
Normal Tissue
RNA Expression

Figure 1 IHC staining of human spleen
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76024/169201_B_9_4_selected.jpg
(Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells in red pulp.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76024/169201_B_9_4_selected.jpg

Figure 2 Cerebral cortex
(Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_B_8_5.jpg
(Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_B_8_5.jpg

Figure 3 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_A_6_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_A_6_6.jpg

Figure 4 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_A_9_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_A_9_8.jpg

Figure 5 High expression in spleen
(Cells in red pulp Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in white pulp Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_B_8_4.jpg
(Cells in red pulp Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in white pulp Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46700/108315_B_8_4.jpg

Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, RPMI-8226, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128604-IRF5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128604-IRF5
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-IRF5 specific antibody (CBACN-323)
- Target
- IRF5
- Immunogen
- N terminus of human IRF5
- Target Species
- Human, Mouse, Rat
- Antibody Clone
- CBACN-323
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.
- Alternative Names
- Interferon Regulatory Factor 5
- Gene ID
- 3663
- UniProt ID
- Q13568
Downloads
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Please select product type
IgG Antibodies
Rabbit Monoclonal Antibodies
IHC Kits & Antibodies
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-3770z | Mouse Anti-IRF5 Recombinant Antibody (clone 34D10) | WB, ELISA, IHC, IP | Mouse IgG1 |
MRO-0870-CN | Recombinant Rabbit Anti-IRF5 Monoclonal Antibody (CBACN-322) | WB, IHC, FC | Rabbit IgG |
MRO-0871-CN | Recombinant Rabbit Anti-IRF5 Monoclonal Antibody (CBACN-323) | WB, IF, IHC, IP, FC | Rabbit IgG |
VS3-WK947 | Rabbit Anti-IRF5 Recombinant Antibody (VS3-WK947) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
VS-0625-FY1455 | Human Anti-IRF5 Recombinant Antibody (clone 2506W1350) | Spiked IP, IF | Human IgG1 |
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For Research Use Only. Not For Clinical Use.
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