Disease related genes, Human disease related genes, Transcription factors
Intracellular
Cell type enhanced (monocytes, Hofbauer cells, Kupffer cells, Macrophages, Collecting duct cells)
Low immune cell specificity
Cell line enhanced (HDLM-2, RPMI-8226, THP-1, U-937)
Homodimer, when phosphorylated (PubMed:25326418, PubMed:18836453). Interacts with TASL (via pLxIS motif); interaction takes place downstream of TLR7, TLR8 or TLR9, leading to its activation (PubMed:32433612). Interacts with MYD88 and TRAF6 (By similarity).
DNA-binding
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.