AbPlus™ Anti-JMJD6 Magnetic Beads (D277)
CAT#: VS-0424-XY163
The AbPlus Anti-JMJD6 Magnetic Beads (D277) is an innovative affinity resin which is bound with anti-JMJD6 specific antibody (D277). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of JMJD6 protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59156/1020_D11_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows strong nuclear positivity in reaction center cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4548/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59156/1043_F5_1_red_green.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59156/993_D11_1_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Glial cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4548/11495_B_7_5.jpg
Normal Tissue
Figure 6 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Peripheral nerve/ganglion
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4548/11495_A_8_3.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4548/11495_A_7_5.jpg
Normal Tissue
Figure 8 Testis
Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Pachytene spermatocytes
Staining:High
Intensity: Strong
Quantity:>75%
Preleptotene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:Medium
Intensity: Strong
Quantity: <25%
Sertoli cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Spermatogonia cells
Staining:High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4548/11495_A_4_6.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4548/11495_A_8_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000070495-JMJD6
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Specifications
- Applications
- Immunoprecipitation, Immunoprecipitation-Mass Spectrometry
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-JMJD6 specific antibody (D277)
- Target
- JMJD6
- Immunogen
- Recombinant human JMJD6 protein
- Target Species
- Human
- Antibody Clone
- D277
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
- Alternative Names
- JMJD6; jumonji domain containing 6; PSR; PTDSR; PTDSR1; bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; histone arginine demethylase JMJD6; jmjC domain-containing protein 6; jumonji domain-containing protein 6; lysyl-hydroxylase JMJD6; pept
- Gene ID
- 23210
- UniProt ID
- Q6NYC1
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Datasheet
MSDS
COA
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See other products for "JMJD6"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-360 | Recombinant Human Anti-Human JMJD6 Antibody, clone D277 | IP, IF, ELISA, IP-MS | IgG |
| FAMAB-1374CQ | Human Anti-JMJD6 Recombinant Antibody (clone APSR-14.4) | IP, WB, IF | Human IgG1 |
| ZG-036R | Mouse Anti-JMJD6 Recombinant Antibody (ZG-036R) | WB, IF | Mouse IgG |
| VS4-WK261 | Mouse Anti-JMJD6 Recombinant Antibody (VS4-WK261) | ELISA, WB, ICC | Mouse IgG |
| VS7-0425-WR170 | Mouse Anti-JMJD6 Recombinant Antibody (VS7-0425-WR170) | WB, IF, ICC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-362 | Recombinant Human Anti-Human JMJD6 Antibody Fab Fragment, clone D279 | IP, IF, ELISA, IP-MS | Fab |
| PFBL-618 | Mouse Anti-JMJD6 Recombinant Antibody; Fab Fragment | WB, IHC, IF, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-618 | Mouse Anti-JMJD6 Recombinant Antibody; scFv Fragment | WB, IHC, IF, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-127 | Recombinant Hamster Anti-JMJD6 Antibody | WB, ELISA, IF, FuncS | IgG |
| PABX-127-F (E) | Recombinant Hamster Anti-JMJD6 Antibody Fab Fragment | WB, ELISA, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-127-S (P) | Recombinant Hamster Anti-JMJD6 Antibody scFv Fragment | WB, ELISA, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1164 | Anti-JMJD6 Immunohistochemistry Kit | IHC |
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