Mouse Anti-KCNQ1 Monoclonal Antibody (clone 5E12)
CAT#: VS7-0425-WR187
This product is a mouse IgG2b antibody that binds to human KCNQ1. The antibody 5E12 can be used for WB and FC assays.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line THP-1
Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane & endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/71107/2061_D8_1_selected.jpg
Normal Tissue
Figure 2 Adrenal gland
High expression in adrenal gland
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_4_5_val_selected.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_5.jpg
Normal Tissue
Figure 4 Thyroid gland
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_3_5.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_4.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (HMC-1, OE19, RPMI-8226, U-266/70, U-937)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000053918-KCNQ1
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Specifications
- Immunogen
- Recombinant human KCNQ1 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human KCNQ1
- Species Reactivity
- Human
- Clone
- 5E12
- Molecule Class
- Ion Channel Protein
- Applications
- WB, FC
- Conjugate
- Unconjugated
- Related Disease
- Long QT syndrome 1 (LQT1); Jervell and Lange-Nielsen syndrome 1 (JLNS1); Atrial fibrillation, familial, 3 (ATFB3)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- LQT; RWS; WRS; LQT1; SQT2; ATFB1; ATFB3; JLNS1; KCNA8; KCNA9; Kv1.9; Kv7.1; KVLQT1
- Gene ID
- 3784
- UniProt ID
- P51787
- Long Name
- Potassium Voltage-Gated Channel Subfamily Q Member 1
- Cellular Localization
- Cell membrane; Cytoplasmic vesicle; Endoplasmic reticulum; Endosome; Membrane
- Post Translation Modifications
- Glycoprotein; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_000209.2
- Function
- Calmodulin-binding; Ion channel; Potassium channel; Voltage-gated channel
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "KCNQ1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0381MZ | Recombinant Mouse Anti-Human KCNQ1 Antibody (clone T38A-11) | ELISA | Mouse antibody |
| VS3-QX633 | Mouse Anti-KCNQ1 Recombinant Antibody (clone 7E1-F6-F10) | WB, IHC, ICC, FC, ELISA | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3736 | Anti-KCNQ1 Immunohistochemistry Kit | IHC |
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