Mouse Anti-KCNQ1 Monoclonal Antibody (clone 5E12) (CAT#: VS7-0425-WR187)
This product is a mouse IgG2b antibody that binds to human KCNQ1. The antibody 5E12 can be used for WB and FC assays.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line THP-1
(Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71107/2061_D8_1_selected.jpg
(Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane & endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71107/2061_D8_1_selected.jpg
Figure 2 Adrenal gland
(High expression in adrenal gland)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_4_5_val_selected.jpg
(High expression in adrenal gland)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_4_5_val_selected.jpg
Figure 3 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_5.jpg
Figure 4 Thyroid gland
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_3_5.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_B_3_5.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/48553/123851_A_7_4.jpg
Figure 6 RNA cell line category: Cell line enhanced (HMC-1, OE19, RPMI-8226, U-266/70, U-937)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000053918-KCNQ1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000053918-KCNQ1
Specifications
- Immunogen
- Recombinant human KCNQ1 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human KCNQ1
- Species Reactivity
- Human
- Clone
- 5E12
- Molecule Class
- Ion Channel Protein
- Applications
- WB, FC
- Conjugate
- Unconjugated
- Related Disease
- Long QT syndrome 1 (LQT1); Jervell and Lange-Nielsen syndrome 1 (JLNS1); Atrial fibrillation, familial, 3 (ATFB3)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- LQT; RWS; WRS; LQT1; SQT2; ATFB1; ATFB3; JLNS1; KCNA8; KCNA9; Kv1.9; Kv7.1; KVLQT1
- Gene ID
- 3784
- UniProt ID
- P51787
- Long Name
- Potassium Voltage-Gated Channel Subfamily Q Member 1
- Cellular Localization
- Cell membrane; Cytoplasmic vesicle; Endoplasmic reticulum; Endosome; Membrane
- Post Translation Modifications
- Glycoprotein; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_000209.2
- Function
- Calmodulin-binding; Ion channel; Potassium channel; Voltage-gated channel
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "KCNQ1"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibodies
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0381MZ | Recombinant Mouse Anti-Human KCNQ1 Antibody (clone T38A-11) | ELISA | Mouse antibody |
| VS3-QX633 | Mouse Anti-KCNQ1 Recombinant Antibody (clone 7E1-F6-F10) | WB, IHC, ICC, FC, ELISA | Mouse IgG2b |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS7-0425-WR187. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, WB
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: WB, IHC, FC, Cyt, ELISA
Application: WB, ELISA, IF, FuncS, Apop, BA
Application: ELISA, IHC, IF, IP, FC, FuncS
Application: ELISA, FuncS
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
