Rabbit Anti-KCTD21 Recombinant Antibody (clone R02-4B5)
CAT#: VS3-FY1754
This R02-4B5 recombinant monoclonal antibody specifically attaches to human KCTD21. It cross-reacts with mouse, rat. This KCTD21 antibody was used in western blot analysis of KCTD21 in K562 lysates. Western blot demonstrated that R02-4B5 recognized a target protein with a molecular weight of 30 kDa.
Tested Data
WB
Figure 1 Anti-KCTD21 Antibody (VS3-FY1754) in WB.
The KCTD21 expression in K562 lysates were detected using the anti-KCTD21 by western blot assay.
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Specifications
- Immunogen
- Recombinant human KCTD21 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat KCTD21
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R02-4B5
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 30 kDa, while the observed molecular weight stands at 30 kDa.
- Related Disease
- Medulloblastoma
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Potassium Channel Tetramerization Domain Containing 21; Potassium Channel Tetramerization Domain-Containing Protein 21; Potassium Channel Tetramerisation Domain Containing 21; BTB/POZ Domain-Containing Protein KCTD21; KCASH2 Protein; KCASH2
- Gene ID
- 283219
- UniProt ID
- Q4G0X4
- Protein Refseq
- XP_006718580.1; XP_006718581.1; XP_047282759.1; XP_054224456.1; XP_054224457.1
- Function
- Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
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