AbPlus™ Anti-KRT4 Magnetic Beads (CBACN-184) (CAT#: VS-0424-XY169)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-KRT4 specific antibody (CBACN-184)

• Target
• KRT4

• Immunogen
• N terminus of human KRT4

• Target Species
• Human

• Antibody Clone
• CBACN-184

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

• Alternative Names
• Keratin 4; CYK4; Keratin, Type II Cytoskeletal 4; Type-II Keratin Kb4; Cytokeratin 4; CK-4; K4

• Gene ID
• 3851

• UniProt ID
• P19013

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