AbPlus™ Anti-KRT4 Magnetic Beads (CBACN-184)
CAT#: VS-0424-XY169
The AbPlus Anti-KRT4 Magnetic Beads (CBACN-184) is an innovative affinity resin which is bound with anti-KRT4 specific antibody (CBACN-184). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of KRT4 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to intermediate filaments.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34881/1576_E1_5_selected.jpg
Normal Tissue
Figure 2 Esophagus
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34881/139056_B_5_1_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human esophagus
Immunohistochemical staining of human esophagus shows distinct cytoplasmic positivity in squamous epithelial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2154/ihc_selected.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34881/139056_A_7_3.jpg
Normal Tissue
Figure 5 Cervix
Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Squamous epithelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/34881/139056_B_9_3.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (HaCaT, SK-BR-3)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000170477-KRT4
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-KRT4 specific antibody (CBACN-184)
- Target
- KRT4
- Immunogen
- N terminus of human KRT4
- Target Species
- Human
- Antibody Clone
- CBACN-184
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
- Alternative Names
- Keratin 4; CYK4; Keratin, Type II Cytoskeletal 4; Type-II Keratin Kb4; Cytokeratin 4; CK-4; K4
- Gene ID
- 3851
- UniProt ID
- P19013
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "KRT4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1989 | Hi-Affi™ Recombinant Rabbit Anti-KRT4 Monoclonal Antibody (DS1989AB) | ICC, IHC-P, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0446-CN | Recombinant Rabbit Anti-KRT4 Monoclonal Antibody (CBACN-184) | WB, IF, IHC, IP, FC | Rabbit IgG |
| MRO-0447-CN | Recombinant Rabbit Anti-KRT4 Monoclonal Antibody (CBACN-185) | WB, IF, IHC | Rabbit IgG |
| VS3-CJ739 | Mouse Anti-KRT4 Recombinant Antibody (clone ABT-CK4) | IHC-P | Mouse IgG1, κ |
| VS3-CJ740 | Rabbit Anti-KRT4 Recombinant Antibody (VS3-CJ740) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
| VS3-FY826 | Recombinant Mouse Anti-KRT4 Antibody (clone 6B5-6H7-9C4) | IHC-P | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3872 | Anti-KRT4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3873 | Anti-Mouse KRT4 Immunohistochemistry Kit | IHC |
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