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KRT4
Anti-KRT4 Recombinant Antibody Products
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP, FC
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Species Reactivity: Dog, Cat, Human, Zebrafish
- Type: Mouse IgG1
- Application: FC, ICC, WB
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: IHC-P
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP, FC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC-P
- AbPlus™ Anti-KRT4 Magnetic Beads (CBACN-184) (VS-0424-XY169)
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- Target: KRT4
- Target Species: Human
- Application: IP, Protein Purification
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, IF, IHC
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- Species Reactivity: Human
- Application: IHC-P, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ICC, IHC-P, IP, WB
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Squamous epithelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HaCaT, SK-BR-3)
Interaction
Heterotetramer of two type I and two type II keratins. Keratin-4 is generally associated with keratin-13.
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