Mouse Anti-KRT6A Recombinant Antibody (clone 7E3D1) (CAT#: VS7-0425-WR268)
This product is a mouse IgG2b antibody that binds to human KRT6A. The antibody 7E3D1 recognizes specific amino acid domain of human KRT6A (AA: 253-352). It can be used for WB, ICC, and FC assays.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/1715_H5_3_cr57fd30536afd1_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/1715_H5_3_cr57fd30536afd1_selected.jpg
Figure 2 IF staining of human cell line hTCEpi
(Immunofluorescent staining of human cell line hTCEpi shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61168/1790_E10_1_selected.jpg
(Immunofluorescent staining of human cell line hTCEpi shows localization to intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61168/1790_E10_1_selected.jpg
Figure 3 IHC staining of human vulva/anal skin
(Immunohistochemical staining of human vulva/anal skin shows strong cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/118500_B_5_8_selected.jpg
(Immunohistochemical staining of human vulva/anal skin shows strong cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/118500_B_5_8_selected.jpg
Figure 4 IHC staining of human oral mucosa
(Immunohistochemical staining of human oral mucosa shows moderate cytoplasmic and membranous positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61168/ihc_selected.jpg
(Immunohistochemical staining of human oral mucosa shows moderate cytoplasmic and membranous positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61168/ihc_selected.jpg
Figure 5 Esophagus
(Squamous epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/118500_B_5_1.jpg
(Squamous epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/118500_B_5_1.jpg
Figure 6 RNA cell line category: Cell line enriched (hTCEpi)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000205420-KRT6A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000205420-KRT6A
Specifications
- Immunogen
- Recombinant human KRT6A (AA: 253-352) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human KRT6A
- Species Reactivity
- Human
- Clone
- 7E3D1
- Molecule Class
- Type II Keratin Family
- Applications
- WB, ICC, FC
- Conjugate
- Unconjugated
- Related Disease
- Pachyonychia congenita 3 (PC3);
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:500 - 1:2000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- K6A; K6C; K6D; PC3; CK6A; CK6C; CK6D; CK-6C; CK-6E; KRT6C; KRT6D
- Gene ID
- 3853
- UniProt ID
- P02538
- Long Name
- Keratin 6A
- Cellular Localization
- Intermediate filament; Keratin
- Post Translation Modifications
- Acetylation
- Protein Refseq
- NP_005545.1
- Function
- Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "KRT6A"
Select a product category from the dropdown menu below to view related products.
Please select product type
Rabbit Monoclonal Antibody Products
IgM Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1991 | Hi-Affi™ Recombinant Rabbit Anti-KRT6A Monoclonal Antibody (DS1991AB) | WB, FC, IP, IHC | IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS7-0425-WR268. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: ELISA, SPR, Inhib, FuncS
Application: ELISA, FC, IF, WB
Application: WB, ELISA, IF, FuncS, Apop, BA
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA
Application: ELISA, PD, Activ, PK, Stim
-1.jpg)
Application: FC
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
