Mouse Anti-KRT6A Recombinant Antibody (clone 7E3D1)
CAT#: VS7-0425-WR268
This product is a mouse IgG2b antibody that binds to human KRT6A. The antibody 7E3D1 recognizes specific amino acid domain of human KRT6A (AA: 253-352). It can be used for WB, ICC, and FC assays.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to intermediate filaments.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/1715_H5_3_cr57fd30536afd1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line hTCEpi
Immunofluorescent staining of human cell line hTCEpi shows localization to intermediate filaments.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61168/1790_E10_1_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human vulva/anal skin
Immunohistochemical staining of human vulva/anal skin shows strong cytoplasmic positivity in epidermal cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/118500_B_5_8_selected.jpg
Subcellular Location and Protein Expression
Figure 4 IHC staining of human oral mucosa
Immunohistochemical staining of human oral mucosa shows moderate cytoplasmic and membranous positivity in squamous epithelial cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61168/ihc_selected.jpg
Normal Tissue
Figure 5 Esophagus
Squamous epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45697/118500_B_5_1.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enriched (hTCEpi)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000205420-KRT6A
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Specifications
- Immunogen
- Recombinant human KRT6A (AA: 253-352) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human KRT6A
- Species Reactivity
- Human
- Clone
- 7E3D1
- Molecule Class
- Type II Keratin Family
- Applications
- WB, ICC, FC
- Conjugate
- Unconjugated
- Related Disease
- Pachyonychia congenita 3 (PC3);
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:500 - 1:2000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- K6A; K6C; K6D; PC3; CK6A; CK6C; CK6D; CK-6C; CK-6E; KRT6C; KRT6D
- Gene ID
- 3853
- UniProt ID
- P02538
- Long Name
- Keratin 6A
- Cellular Localization
- Intermediate filament; Keratin
- Post Translation Modifications
- Acetylation
- Protein Refseq
- NP_005545.1
- Function
- Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Reconstitution Buffer
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "KRT6A"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1991 | Hi-Affi™ Recombinant Rabbit Anti-KRT6A Monoclonal Antibody (DS1991AB) | WB, FC, IP, IHC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-1043F | Mouse Anti-KRT6A Recombinant Antibody (clone LL020) | FC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX661 | Mouse Anti-KRT6A Recombinant Antibody (clone A2A12) | WB, IHC | Mouse IgG1 |
| VS3-QX662 | Mouse Anti-KRT6A Recombinant Antibody (clone A2B2) | WB, IHC | Mouse IgG1 |
| VS3-CJ293 | Mouse Anti-KRT6A Recombinant Antibody (VS3-CJ293) | WB, IHC | |
| VS3-CJ294 | Mouse Anti-KRT6A Recombinant Antibody (clone SBT-CK6) | WB, IHC-P | Mouse IgG |
| VS3-FY829 | Recombinant Mouse Anti-KRT6A Antibody (clone 4F10-6D6-3C1) | IHC-P | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3879 | Anti-KRT6A Immunohistochemistry Kit | IHC | |
| VS-0525-XY3880 | Anti-Mouse KRT6A Immunohistochemistry Kit | IHC | |
| VS-0525-XY3881 | Anti-Human KRT6A Immunohistochemistry Kit | IHC | |
| VS-0525-XY3882 | Anti-Rat KRT6A Immunohistochemistry Kit | IHC |
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