AbPlus™ Anti-LGMN Magnetic Beads (VS-0724-YC672)
CAT#: VS-0724-YC672
The AbPlus Anti-LGMN Magnetic Beads (VS-0724-YC672) is an innovative affinity resin which is bound with anti-LGMN specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of LGMN protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1426/1766_F1_3_selected.jpg
Normal Tissue
Figure 2 IHC staining of human placenta
High expression. RNA expression: 262.1 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1426/ihc_selected.jpg
Normal Tissue
Figure 3 IHC staining of human pancreas
Low expression. RNA expression: 37.9 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1426/5643_A_2_3_val_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1426/5643_B_9_5.jpg
Normal Tissue
Figure 5 Colon
Enterocytes
Staining: Low
Intensity: Moderate
Quantity: <25%
Goblet cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1426/5643_A_7_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1426/5643_A_7_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1426/5643_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1426/5643_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (RPMI-8226, U-266/70)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100600-LGMN
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-LGMN specific antibody
- Target
- LGMN
- Immunogen
- Recombinant pig legumain, aa 1-433.
- Target Species
- Pig
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the cysteine peptidase family C13 that plays an important role in the endosome/lysosomal degradation system. The encoded inactive preproprotein undergoes autocatalytic removal of the C-terminal inhibitory propeptide to generate the active endopeptidase that cleaves protein substrates on the C-terminal side of asparagine residues. Mice lacking the encoded protein exhibit defects in the lysosomal processing of proteins resulting in their accumulation in the lysosomes, and develop symptoms resembling hemophagocytic lymphohistiocytosis.
- Alternative Names
- AEP; Prsc1
- Gene ID
- 19141
- UniProt ID
- O89017
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CITATIONS
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "LGMN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2047 | Hi-Affi™ Recombinant Rabbit Anti-LGMN Monoclonal Antibody (DS2047AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY1758 | Rabbit Anti-LGMN Recombinant Antibody (clone R06-7G1) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1242 | Anti-LGMN Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4010 | Anti-Human LGMN Immunohistochemistry Kit | IHC |
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