AbPlus™ Anti-LXN Magnetic Beads (VS-0724-YC60)
CAT#: VS-0724-YC60
The AbPlus Anti-LXN Magnetic Beads (VS-0724-YC60) is an innovative affinity resin which is bound with anti-LXN specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of LXN protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/14179/1134_H3_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human urinary bladder
High expression. RNA expression: 97.7 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/14179/33185_A_6_5_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human cerebral cortex
Low expression. RNA expression: 4.4 nTPM
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/14179/33185_B_9_5_val_selected.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25128/55430_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25128/55430_A_8_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25128/55430_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25128/55430_A_6_6.jpg
Normal Tissue
Figure 8 Prostate
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25128/55430_A_2_5.jpg
Normal Tissue
Figure 9 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/25128/55430_A_9_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enriched (hTERT-RPE1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000079257-LXN
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-LXN specific antibody
- Target
- LXN
- Immunogen
- Recombinant human Latexin/LXN, aa 2-222.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. The encoded protein, latexin, downregulates the population size of hematopoietic stem cells. This protein is found to be downregulated in cancer cells because of promoter hypermethylation.
- Alternative Names
- ECI; TCI
- Gene ID
- 56925
- UniProt ID
- Q9BS40
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CITATIONS
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "LXN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0334MZ | Chicken Anti-LXN Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
| BRD-0923MZ | Chicken Anti-Latexin Polyclonal IgY | ELISA, ICC, IHC, IF | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2103 | Hi-Affi™ Recombinant Rabbit Anti-Lxn Monoclonal Antibody (DS2103AB) | ELISA | IgG |
| MOR-4310 | Hi-Affi™ Recombinant Rabbit Anti-LXN Monoclonal Antibody (SI399DS) | WB, ELISA, ICC, IF, IF, IP, FC | IgG |
| MOR-4311 | Hi-Affi™ Recombinant Rabbit Anti-Lxn Monoclonal Antibody (SI400DS) | FC | IgG |
| MOR-4312 | Hi-Affi™ Recombinant Rabbit Anti-Lxn Monoclonal Antibody (SI401DS) | FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY1022 | Mouse LXN Recombinant Antibody (clone 199CT6.1.2) | WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4129 | Anti-LXN Immunohistochemistry Kit | IHC | |
| VS-0525-XY4130 | Anti-Mouse LXN Immunohistochemistry Kit | IHC |
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