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LXN

Anti-LXN Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. The encoded protein, latexin, downregulates the population size of hematopoietic stem cells. This protein is found to be downregulated in cancer cells because of promoter hypermethylation.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (granulocytes, Respiratory ciliated cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enriched (hTERT-RPE1)

Molecular function

Heparin-binding, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor

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