Recombinant Anti-MIOX (AA 9-21 x AA 268-279) Biparatopic Antibody, Tandem scFv (CAT#: VS-0525-YC125)
The Recombinant Anti-MIOX (AA 9-21 x AA 268-279) Biparatopic Antibody, Tandem scFv is a biparatopic antibody (bpAb) designed for dual epitope binding to MIOX. This bpAb features tandem scFv arms that exhibit simultaneous, high-affinity binding to amino acids 9-21 (sequence: PSLVYRPDCDPEV) and amino acids 268-279 (sequence: RPYYQGLIDKYC).
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in kidney
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39451/ihc_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39451/ihc_selected.jpg
Figure 2 Low expression in pancreas
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39451/146537_A_1_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39451/146537_A_1_3_val_selected.jpg
Figure 3 Cerebral cortex
(Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39451/146537_B_7_5.jpg
(Neuropil Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39451/146537_B_7_5.jpg
Figure 4 Kidney
(Proximal tubules (cell body) Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39451/146537_A_8_5.jpg
(Proximal tubules (cell body) Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39451/146537_A_8_5.jpg
Figure 5 RNA cell line category: Cell line enhanced (HDLM-2, Hep G2, Karpas-707, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100253-MIOX
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100253-MIOX
Specifications
- Host Animal 1
- Mouse
- Host Animal 2
- Mouse
- Specificity
- Human MIOX
- Species Reactivity
- Human, Mouse, Rat
- Type
- Tandem scFv
- Valency
- 1 + 1
- Epitope 1
- aa 9-21, PSLVYRPDCDPEV
- Epitope 2
- aa 268-279, RPYYQGLIDKYC
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA, IHC, WB
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- Myo-Inositol Oxygenase
Target
- Introduction
- The enzyme MI oxygenase (MIOX; EC 1.13.99.1) is a key regulator of inositol levels, catalyzing the first committed step in the glucuronate-xylulose pathway, the only known pathway for MI catabolism. MIOX is almost exclusively expressed in the kidneys, where it is localized to the proximal tubular epithelial cells.
- Alternative Names
- ALDRL6
- Gene ID
- 55586
- UniProt ID
- Q9UGB7
Downloads
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IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1925MZ | Recombinant Mouse Anti-Human MIOX Antibody (clone 3G5) | WB | Mouse antibody |
| HPAB-0074CQ | Mouse Anti-MIOX Recombinant Antibody (HPAB-0074CQ) | ELISA, WB, IHC, FuncS | Mouse IgG2b, κ |
| HPAB-0075CQ | Mouse Anti-MIOX Recombinant Antibody (HPAB-0075CQ) | ELISA, WB, IHC, FuncS | Mouse IgG2b, κ |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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