AbPlus™ Anti-MTHFS Magnetic Beads (VS-0724-YC708) (CAT#: VS-0724-YC708)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-MTHFS specific antibody

• Target
• MTHFS

• Immunogen
• Recombinant human MTHFS fragment derived from E. coli.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

• Alternative Names
• Methenyltetrahydrofolate Synthetase; 5,10-Methenyltetrahydrofolate Synthetase (5-Formyltetrahydrofolate Cyclo-Ligase); 5-Formyltetrahydrofolate Cyclo-Ligase; Methenyl-THF Synthetase; 5,10-Methenyl-Tetrahydrofolate Synthetase; 5,10-Methenyltetrahydrofolate Synthetase; EC 6.3.3.2; HsT19268;

• Gene ID
• 10588

• UniProt ID
• P49914

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