Rabbit Anti-MYO19 Recombinant Antibody (clone R03-8A7)
CAT#: VS3-FY1784
This R03-8A7 recombinant monoclonal antibody demonstrated a greater affinity to human MYO19. It cross-reacts with mouse. The MYO19 antibody has been teted positive by western blot analysis of MYO19 in K562, 3T3, Hela lysates.
Tested Data
Gene Expression
WB
Figure 1 Anti-MYO19 Antibody (VS3-FY1784) in WB.
The MYO19 expression in K562, 3T3, Hela lysates were detected using the anti-MYO19 by western blot assay.
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Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21415/188_D5_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol & mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59715/1013_G10_1_selected.jpg
Normal Tissue
Figure 3 IHC staining of human small intestine
Immunohistochemical staining of human small intestine shows strong membranous and cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59715/159906_A_4_2_selected.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59715/159906_A_7_8.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59715/159906_A_7_3.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59715/159906_A_6_6.jpg
Normal Tissue
Figure 7 Skin
Fibroblasts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Keratinocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Melanocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/59715/159846_B_9_1.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000278259-MYO19
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Specifications
- Immunogen
- Recombinant human MYO19 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse MYO19
- Species Reactivity
- Human, Mouse
- Clone
- R03-8A7
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 109 kDa, while the observed molecular weight stands at 109 kDa.
- Related Disease
- Glycosylphosphatidylinositol Biosynthesis Defect 11 and Cleft Palate, Isolated
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Myosin XIX; Myosin Head Domain-Containing Protein 1; Myosin Head Domain Containing 1; MYOHD1; Unconventional Myosin-XIX
- Gene ID
- 80179
- UniProt ID
- Q96H55
- Sequence Similarities
- Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
- Cellular Localization
- Cytoplasm, Cytoskeleton, Membrane, Mitochondrion, Mitochondrion outer membrane
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q96H55)
Modification sites at neXtProt (NX_Q96H55)
- Protein Refseq
- XP_011523588.1; XP_011523589.1; XP_011523592.1; XP_016880646.1; XP_016880647.1
- Function
- Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane.
Motor protein that moves towards the plus-end of actin filaments (By similarity).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "MYO19"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2350 | Hi-Affi™ Recombinant Rabbit Anti-MYO19 Monoclonal Antibody (DS2350AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1430 | Anti-MYO19 Immunohistochemistry Kit | IHC |
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