Rabbit Anti-NDEL1 Recombinant Antibody (clone R05-1D0) (CAT#: VS3-FY2043)
The R05-1D0 recombinant monoclonal antibody has been genetically engineered to specifically target human NDEL1. It cross-reacts with mouse. Applications Tested: The NDEL1 antibody has been tested by western blot analysis of NDEL1 in Hela, A549, HL-60, U251, U87-MG lysates.
Specific Inquiry
WB
Figure 1 Anti-NDEL1 Antibody (VS3-FY2043) in WB.
The NDEL1 expression in Hela, A549, HL-60, U251, U87-MG lysates were detected using the anti-NDEL1 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human NDEL1
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse NDEL1
- Species Reactivity
- Human, Mouse
- Clone
- R05-1D0
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 38 kDa, while the observed molecular weight stands at 38 kDa.
- Related Disease
- Lissencephaly and Miller-Dieker Lissencephaly Syndrome
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- NudE Neurodevelopment Protein 1 Like 1; Mitosin-Associated Protein 1; Protein Nudel; MITAP1; NUDEL; EOPA; NudE Nuclear Distribution Gene E Homolog (A. Nidulans)-Like 1; NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1
- Gene ID
- 81565
- UniProt ID
- Q9GZM8
- Sequence Similarities
- Belongs to the nudE family.
- Cellular Localization
- Centromere, Chromosome, Cytoplasm, Cytoskeleton, Kinetochore, Microtubule
- Post Translation Modifications
- Phosphorylated in mitosis.
Can be phosphorylated by CDK1, CDK5 and MAPK1.
Phosphorylation by CDK5 promotes interaction with KATNA1 and YWHAE.
(Q9GZM8-NDEL1_HUMAN)
Palmitoylation at Cys-273 reduces affinity for dynein. (Q9GZM8-NDEL1_HUMAN)
Modification sites at PhosphoSitePlus (Q9GZM8)
Modification sites at neXtProt (NX_Q9GZM8)
Glycosylation from GlyGen (Q9GZM8) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_016880672.1; XP_016880673.1; XP_016880675.1; XP_016880677.1; XP_047292816.1
- Function
- May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "NDEL1"
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2388 | Hi-Affi™ Recombinant Rabbit Anti-NDEL1 Monoclonal Antibody (DS2388AB) | WB, IHC | IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1117-CN | Recombinant Rabbit Anti-NDEL1 Monoclonal Antibody (JG38-63) | WB, IHC | Rabbit IgG |
| VS3-WK484 | Rabbit Anti-NDEL1 Recombinant Antibody (clone JG38-63) | WB, ELISA | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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