Rabbit Anti-NF2 Recombinant Antibody (VS13-YC788)

Name: Rabbit Anti-NF2 Recombinant Antibody (VS13-YC788)
SKU: VS13-YC788
Rating: 5 (1 reviews)

CAT#: VS13-YC788

The Rabbit Anti-NF2 Recombinant Antibody is specific for human, mouse and rat NF2. NF2 encodes a protein similar to ERM family members, linking cytoskeleton with cell membrane proteins, with mutations associated with neurofibromatosis type II. The anti-NF2 antibody can be used for Western blot (1/500-1/1000), Immunoprecipitation (1/20).

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3097/if_selected.jpg

Subcellular Location Figure 2 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, plasma membrane & cytosol.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5385/639_D4_5_selected.jpg

Normal Tissue Figure 3 IHC staining of human hippocampus

Immunohistochemical staining of human hippocampus shows strong nucleolar and moderate cytoplasmic positivity in neuronal cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5385/19505_B_7_6_selected.jpg

Normal Tissue Figure 4 Lymph node

Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5385/19505_A_7_8.jpg

Normal Tissue Figure 5 Liver

Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5385/19505_A_8_4.jpg

Normal Tissue Figure 6 Kidney

Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5385/19505_A_7_5.jpg

Normal Tissue Figure 7 Testis

Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25% Round or early spermatids Staining: Low Intensity: Moderate Quantity: <25% Spermatogonia cells Staining: High Intensity: Strong

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5385/19505_A_6_6.jpg

RNA Expression Figure 8 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000186575-NF2

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Specifications

Immunogen
Recombinant human NF2.

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human, Mouse and Rat NF2

Species Reactivity
Human, Mouse, Rat

Applications
WB, IP

Conjugate
NONE

Product Property

Clonality
Monoclonal

Purification
Affinity Chromatography purified

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Buffer
50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.

Preservative
0.01% Sodium azide

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Shipping
Shipping with ice pack.

Applications

Application Notes
Western blot (WB): 1/500-1/1000
Immunoprecipitation (IP): 1/20

Target

Alternative Names
Neurofibromin 2; Schwannomin; Neurofibromin 2 (Bilateral Acoustic Neuroma); Moesin-Ezrin-Radixin-Like Protein; Moesin-Ezrin-Radixin Like; Schwannomerlin; SCH;

Gene ID
4771

UniProt ID
P35240

Long Name
Neurofibromin 2

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS13-YC788.pdf

MSDS

MSDS - VS13-YC788.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Secondary Antibody

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Isotype Control

CAT
Product Name

See other products for "NF2"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
MOB-3137z	Mouse Anti-NF2 Recombinant Antibody (clone 43G7)	WB, IP, IF, ELISA	Mouse IgG2b, κ
MOB-0222CT	Recombinant Mouse anti-Human NF2 Monoclonal antibody (nBcdbn73940)	ICC, IF, WB
VS3-FY1031	Recombinant Rabbit Anti-NF2 Antibody (clone R07-1A6)	WB, IP	Rabbit IgG

CAT	Product Name	Application	Type
MOR-2428	Hi-Affi™ Recombinant Rabbit Anti-NF2 Monoclonal Antibody (DS2428AB)	WB, IP	IgG

CAT	Product Name	Application	Type
VS-0325-XY1486	Anti-NF2 Immunohistochemistry Kit	IHC

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