Human Anti-NoV VP1 Recombinant Antibody (VS-0126-FY86)
CAT#: VS-0126-FY86
The antibody is a broadly cross-reactive human monoclonal antibody (originally IgA isotype) isolated from a donor with a history of GII.4 Sydney 2012 Norovirus infection. It exhibits broad binding and neutralization activity against multiple Genogroup II (GII) genotypes, including GII.3, GII.4, GII.6, GII.13, and GII.17.
Specifications
- Immunogen
- Natural infection with Human Norovirus GII.4 Sydney 2012.
- Host Species
- Human
- Type
- Human IgG
- Antibody Isotype
- IgG
- Specificity
- Broadly reactive to GII genotypes (GII.3, GII.4, GII.6, GII.13, GII.17).
- Species Reactivity
- Norovirus (NoV)
- Applications
- ELISA, Neutralization
Product Property
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- ELISA: The EC₅₀ value is approximately 2-3 nM against the P-domains of GII.4, GII.6, and GII.17.
Target
- Alternative Names
- VP1, Major Capsid Protein
- Long Name
- Norovirus Major Capsid Protein
- Function
- The major capsid protein of Norovirus. It assembles into icosahedral particles and is responsible for binding to histo-blood group antigens (HBGAs) on host cells. It contains the primary antigenic determinants that evolve to evade host immunity.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "NoV VP1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2341CQ | Recombinant Mouse Anti-NoV VP1 Antibody (MRO-2341CQ) | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2342CQ | Recombinant Mouse Anti-NoV VP1 Antibody | ELISA | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0126-FY126 | Human Anti-NoV VP1 Recombinant Antibody (clone VX22) | Neut, Block | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0126-FY130 | Human Anti-NoV VP1 Recombinant Antibody (clone 16E10) | Neut, ELISA | Human IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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