AbPlus™ Anti-NR3C1 Magnetic Beads (VS-0724-YC345)
CAT#: VS-0724-YC345
The AbPlus Anti-NR3C1 Magnetic Beads (VS-0724-YC345) is an innovative affinity resin which is bound with anti-NR3C1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of NR3C1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4248/78_E8_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, cytosol & mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10435/if_selected.jpg
Normal Tissue
Figure 3 Testis
Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Peritubular cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: Medium Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10435/26792_A_6_6.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10435/26792_A_7_8.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10435/26792_A_8_4.jpg
Normal Tissue
Figure 6 Pancreas
Exocrine glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10435/26792_A_3_3.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10435/26792_A_9_5.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113580-NR3C1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-NR3C1 specific antibody
- Target
- NR3C1
- Immunogen
- Synthetic peptide corresponding to the center region of the human NR3C1.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
- Alternative Names
- Nuclear Receptor Subfamily 3 Group C Member 1; Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor); Glucocorticoid Receptor; GRL; GR; Nuclear Receptor Subfamily 3, Group C, Member 1;
- Gene ID
- 2908
- UniProt ID
- P04150
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "NR3C1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0756MZ | Recombinant Mouse Anti-Human NR3C1 Antibody (clone 9F0) | ELISA | Mouse antibody |
| ZG-0489U | Rabbit Anti-NR3C1 Recombinant Antibody (clone 2D8) | ELISA, WB, FC | Rabbit IgG |
| VS3-WK398 | Rabbit Anti-NR3C1 Recombinant Antibody (clone JF0952) | WB, FC | Rabbit IgG |
| VS3-XY1182 | Mouse Anti-NR3C1 Recombinant Antibody (clone 6E6) | ELISA, WB, IHC, FC, ICC | Mouse IgG1 |
| VS3-FY1067 | Recombinant Rabbit Anti-Nr3C1 Antibody (clone R04-8C8) | WB, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1788CQ | Recombinant Mouse Anti-NR3C1 Antibody (BuGR2) | WB, Neut, ChIP, FC, GS, ICC, IF, IHC, IHC-P, IP | IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2493 | Hi-Affi™ Recombinant Rabbit Anti-NR3C1 Monoclonal Antibody (DS2493AB) | WB, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC840 | CytoStream™ Mouse Anti-NR3C1 Recombinant Antibody (VS13-YC840) | WB, IHC-P, FC, ICC, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1514 | Anti-NR3C1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4960 | Anti-Mouse NR3C1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4959 | Anti-Human NR3C1 Immunohistochemistry Kit | IHC |
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