Human Anti-NTF3 Recombinant Antibody (clone NTF30037)
CAT#: VS-0326-FY196
This is a first-in-class, fully human neutralizing monoclonal antibody developed through an innovative long VH CDR3 phage display library. It exhibits high specificity for Neurotrophic factor 3 (NTF3), effectively blocking its interaction with TrkA, TrkB, and TrkC receptors.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32001/1394_F5_5_selected.jpg
Normal Tissue
Figure 2 IHC staining of human caudate
Immunohistochemical staining of human caudate shows strong cytoplasmic positivity in glial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32001/162193_B_8_7_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32001/162193_B_8_5.jpg
Normal Tissue
Figure 4 Caudate
Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32001/162193_B_8_7.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32001/162193_A_7_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32001/162193_A_7_5.jpg
Normal Tissue
Figure 7 Testis
Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32001/162193_A_6_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (BJ hTERT+, BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, HBF TERT88, RT4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185652-NTF3
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Specifications
- Immunogen
- Recombinant human CBD-NTF3 and Avi-His-NTF3 (produced in HEK293 and CHO cells)
- Host Species
- Human
- Type
- Human IgG1
- Antibody Isotype
- IgG1
- Specificity
- Specific to Human NTF3; demonstrated high selectivity against NGF, BDNF, and NTF4
- Species Reactivity
- Human
- Clone
- NTF30037
- Applications
- Inhibition
- Related Disease
- Neurodegenerative diseases, Hearing loss
Product Property
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "NTF3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0841MZ | Chicken Anti-NTF3 Polyclonal IgY | ELISA | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1801CQ | Recombinant Mouse Anti-NTF3 Antibody (NEUT-1801CQ) | ELISA, Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1802CQ | Recombinant Mouse Anti-NTF3 Antibody (8F23) | Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1803CQ | Recombinant Mouse Anti-NTF3 Antibody (CBL148) | ELISA, Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1804CQ | Recombinant Mouse Anti-NTF3 Antibody (CBL149) | Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1805CQ | Recombinant Mouse Anti-NTF3 Antibody (CBL468) | ELISA(Cap), Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0806-CN | Mouse Anti-NTF3 Recombinant Antibody (clone 3W3) | ELISA, Neut | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0806-CN-S(P) | Mouse Anti-NTF3 Recombinant Antibody (clone 3W3); scFv Fragment | ELISA, Neut | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0806-CN-F(E) | Mouse Anti-NTF3 Recombinant Antibody (clone 3W3); Fab Fragment | ELISA, Neut | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5005 | Anti-NTF3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5006 | Anti-Human NTF3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5007 | Anti-Mouse NTF3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC241 | Recombinant Anti-NTF3 Eliminating Antibody, pH-Sensitive (3W3 var.) | Antigen-Sweeping In Vivo. | Mouse IgG |
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