Rabbit Anti-NUS1 Recombinant Antibody (clone R01-3K8)
CAT#: VS3-FY1801
This R01-3K8 recombinant monoclonal antibody exhibits specific targeting for human NUS1. It cross-reacts with mouse, rat. The specificity of the nogo B receptor antibody was confirmed by western blot analysis of nogo B receptor in K562, 3T3, Hela lysates.
Gene Expression
Tested Data
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27504/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human rectum
Immunohistochemical staining of human rectum shows distinct positivity in blood vessels and adipocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27504/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27504/61495_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27504/61431_A_7_3.jpg
Normal Tissue
Figure 5 Skin
Fibroblasts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Keratinocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Langerhans Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Melanocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/27504/61495_B_7_1.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000153989-NUS1
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WB
Figure 1 Anti-NUS1 Antibody (VS3-FY1801) in WB.
The Nogo B receptor expression in K562, 3T3, Hela lysates were detected using the anti-Nogo B Receptor by western blot assay.
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Specifications
- Immunogen
- Synthetic peptide of human Nogo B receptor
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat NUS1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R01-3K8
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 33 kDa, while the observed molecular weight stands at 33 kDa.
- Related Disease
- Cancer
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- NUS1 Dehydrodolichyl Diphosphate Synthase Subunit; Nogo-B Receptor; Nuclear Undecaprenyl Pyrophosphate Synthase 1 Homolog; Di-Trans,Poly-Cis-Decaprenylcistransferase; C6orf68; NgBR; Nuclear Undecaprenyl Pyrophosphate Synthase 1 Homolog (S. Cerevisiae); Dehydrodolichyl Diphosphate Synthase Complex Subunit NUS1; Transport And Golgi Organization 14 Homolog (Drosophila)
- Gene ID
- 116150
- UniProt ID
- Q96E22
- Sequence Similarities
- Belongs to the UPP synthase family.
- Cellular Localization
- Endoplasmic reticulum, Membrane
- Post Translation Modifications
- Glycosylation at Asn144 and Asn271 (NX_Q96E22 [NX_Q96E22-1])
Modification sites at PhosphoSitePlus (Q96E22)
Glycosylation from GlyGen (Q96E22) 2 sites
- Protein Refseq
- NP_612468.1
- Function
- Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "NUS1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2529 | Hi-Affi™ Recombinant Rabbit Anti-NUS1 Monoclonal Antibody (DS2529AB) | WB | IgG |
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