AbPlus™ Anti-P4HB Magnetic Beads (VS-0724-YC1441)
CAT#: VS-0724-YC1441
The AbPlus Anti-P4HB Magnetic Beads (VS-0724-YC1441) is an innovative affinity resin which is bound with anti-P4HB specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of P4HB protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18884/if_selected.jpg
Normal Tissue
Figure 2 Small intestine
High expression in small intestine
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18884/43373_A_4_2_val_selected.jpg
Normal Tissue
Figure 3 Testis
Leydig cells Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18884/43373_A_4_6.jpg
Normal Tissue
Figure 4 Duodenum
Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Glands of Brunner Staining: High Intensity: Strong Quantity:>75% Goblet cells Staining: High Intensity: Strong Quantity:>75% Paneth cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18884/43373_A_9_2.jpg
Normal Tissue
Figure 5 Colon
Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Fibroblasts Staining: High Intensity: Strong Goblet cells Staining: High Intensity: Strong Quantity:>75% Mucosal lymphoid cells Staining: Medium Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18884/43373_A_7_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18884/43373_A_7_4.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185624-P4HB
❮
❯
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-P4HB specific antibody
- Target
- P4HB
- Immunogen
- Recombinant human P4HB/ERBA2L, aa 1-505.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]
- Alternative Names
- Prolyl 4-Hydroxylase Subunit Beta; Procollagen-Proline, 2-Oxoglutarate 4-Dioxygenase (Proline 4-Hydroxylase), Beta Polypeptide; Protein Disulfide Isomerase Family A, Member 1; Protein Disulfide Isomerase-Associated 1; Cellular Thyroid Hormone-Binding Protein; Prolyl 4-Hydroxylase, Beta Polypeptide; Collagen Prolyl 4-Hydroxylase Beta; EC 5.3.4.1; ERBA2L; PO4DB; PDIA1; P55; PDI; Procollagen-Proline, 2-Oxoglutarate 4-Dioxygenase (Proline 4-Hydroxylase), Beta Polypeptide (Protein Disulfide Isomerase; Thyroid Hormone Binding Protein P55); Procollagen-Proline, 2-Oxoglutarate 4-Dioxygenase (Proline 4-Hydroxylase), Beta Polypeptide (Protein Disulfide Isomerase-Associated 1);
- Gene ID
- 5034
- UniProt ID
- P07237
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0724-YC1441. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "P4HB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1426z | Mouse Anti-P4HB Recombinant Antibody (clone 31F5) | WB, IP, IF, IHC, ELISA | Mouse IgG1, κ |
| MOB-2363CT | Recombinant Mouse anti-Cow P4HB Monoclonal antibody (nBcdbn72940) | FC | |
| VS3-CJ460 | Mouse Anti-P4HB Recombinant Antibody (VS3-CJ460) | WB | Mouse IgG |
| VS3-FY1086 | Recombinant Mouse Anti-P4HB Antibody (clone 3F12C11D2) | ELISA, WB, IHC, ICC, FC | Mouse IgG2a |
| VS3-FY1087 | Recombinant Mouse Anti-P4HB Antibody (clone 5D12A4E5) | ELISA, WB, IHC, ICC, FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1823CQ | Recombinant Mouse Anti-P4hb Antibody (RL77) | BL, ELISA, FC, GSA, ICC, IF, IHC, IHC-P, IP, WB | IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1824CQ | Recombinant Mouse Anti-P4hb Antibody (RL90) | BL, ELISA, FC, ICC, IF, IHC, IHC-Fr, IHC-P, IP, WB | IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2568 | Hi-Affi™ Recombinant Rabbit Anti-P4HB Monoclonal Antibody (DS2568AB) | WB, IHC, ICC, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5140 | Anti-Mouse P4HB Immunohistochemistry Kit | IHC | |
| VS-0525-XY5141 | Anti-Rabbit P4HB Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: Neut, ELISA, Inhib, ICC, WB
Application: WB, ELISA, FC, IHC, IP
-3.jpg)
Application: ELISA, WB
-2.png)
Application: ELISA
Application: ELISA, Cyt, PP, Inhib
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
