AbPlus™ Anti-PAX2 Magnetic Beads (VS-0724-YC344) (CAT#: VS-0724-YC344)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-PAX2 specific antibody

• Target
• PAX2

• Immunogen
• Synthetic peptide corresponding to the center region of the human PAX2.

• Target Species
• Human, Mouse

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]

• Alternative Names
• Paired Box 2; Paired Box Homeotic Gene 2; Paired Box Protein Pax-2; Paired Box Gene 2; FSGS7; PAPRS;

• Gene ID
• 5076

• UniProt ID
• Q02962

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