Rabbit Anti-PAX2 Recombinant Antibody (clone R04-3H7) (CAT#: VS3-XY3457)
The antibody is a recombinant rabbit antibody binding with PAX2 (Paired box 2), which has a critical role in the development of the urogenital tract, the eyes, and the CNS. This product recognizes human and mouse PAX2. It has been detected using Western Blot, Immunohistochemistry-Paraffin and Flow cytometry. The recommended dilutions of Western blot, Immunohistochemistry-Paraffin and Flow cytometry is 1/500-1/1000, 1/50-1/100 and 1/50-1/100, respectively.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line EFO-21
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47704/1830_D12_69_selected.jpg
(Immunofluorescent staining of human cell line EFO-21 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47704/1830_D12_69_selected.jpg
Figure 2 Endometrium 1
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13024/164460_B_4_3_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13024/164460_B_4_3_val_selected.jpg
Figure 3 Colon
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47704/164461_A_7_3.jpg
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47704/164461_A_7_3.jpg
Figure 4 High expression in epididymis
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47704/164461_A_3_6.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/47704/164461_A_3_6.jpg
Figure 5 RNA cell line category: Group enriched (AN3-CA, EFO-21, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000075891-PAX2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000075891-PAX2
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse PAX2
- Species Reactivity
- Human, Mouse
- Clone
- R04-3H7
- Applications
- WB, IHC-P, FC
- Related Disease
- Papillorenal Syndrome; Focal Segmental Glomerulosclerosis 7
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
FC: 1/50-1/100
Target
- Alternative Names
- FSGS7; PAPRS; PAX-2
- Gene ID
- 5076
- UniProt ID
- Q02962
- Long Name
- Paired box 2
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q02962)
Modification sites at neXtProt (NX_Q02962)
- Protein Refseq
- NP_001291498.1; NP_000269.3
- Function
- Transcription factor that may have a role in kidney cell differentiation (PubMed:24676634).
Has a critical role in the development of the urogenital tract, the eyes, and the CNS.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "PAX2"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1554CT | Recombinant Mouse anti-Human PAX2 Monoclonal antibody (EML548) | WB | |
| MRO-1169-CN | Recombinant Rabbit Anti-PAX2 Monoclonal Antibody (CBACN-426) | WB, IHC | Rabbit IgG |
| VS3-WK861 | Rabbit Anti-PAX2 Recombinant Antibody (VS3-WK861) | WB, IHC | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2600 | Hi-Affi™ Recombinant Rabbit Anti-PAX2 Monoclonal Antibody (DS2600AB) | WB, FC, IHC | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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