Rabbit Anti-PEX11B Recombinant Antibody (clone R09-7B4) (CAT#: VS3-FY1828)
Clone R09-7B4 is a rabbit recombinant monoclonal antibody that specifically directed against human PEX11B. It cross-reacts with mouse. This PEX11B antibody was verified by western blot analysis of Peroxiredoxin 4 in 293T lysates.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17150/1871_G11_21_cr5b4882c63994d_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17150/1871_G11_21_cr5b4882c63994d_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50104/112405_B_9_5.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50104/112405_B_9_5.jpg
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50104/112405_A_7_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50104/112405_A_7_3.jpg
Figure 4 Liver
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50104/112405_A_9_4.jpg
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50104/112405_A_9_4.jpg
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50104/112405_A_9_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50104/112405_A_9_5.jpg
Figure 6 Testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50104/112405_A_4_6.jpg
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50104/112405_A_4_6.jpg
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131779-PEX11B
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131779-PEX11B
Specifications
- Immunogen
- Synthetic peptide of human PEX11B
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse PEX11B
- Species Reactivity
- Human, Mouse
- Clone
- R09-7B4
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 28 kDa, while the observed molecular weight stands at 28 kDa.
- Related Disease
- Peroxisome Biogenesis Disorder 14B and Neonatal Adrenoleukodystrophy
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Peroxisomal Biogenesis Factor 11 Beta; Peroxisomal Biogenesis Factor 11B; Protein PEX11 Homolog Beta; Peroxin-11B; PEX11-BETA; Peroxisomal Membrane Protein 11B; PEX14B
- Gene ID
- 8799
- UniProt ID
- O96011
- Sequence Similarities
- Belongs to the peroxin-11 family.
- Cellular Localization
- Membrane, Peroxisome
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (O96011)
Modification sites at neXtProt (NX_O96011)
Glycosylation from GlyGen (O96011) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001171724.1; NP_003837.1
- Function
- May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane.
Promotes membrane protrusion and elongation on the peroxisomal surface.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2664 | Hi-Affi™ Recombinant Rabbit Anti-PEX11B Monoclonal Antibody (DS2664AB) | WB | IgG |
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