Rabbit Anti-Pip5K1C Recombinant Antibody (clone R06-3J3) (CAT#: VS3-FY1834)
Clone R06-3J3 is a rabbit recombinant monoclonal antibody that specifically directed against human Pip5K1C. It cross-reacts with mouse. It is suitable for use in a variety of assays, including WB, IP. Applications Tested: The PIP5K1C antibody has been tested by western blot analysis of PIP5KI gamma in mouse brain lysates.
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WB
Figure 1 Anti-Pip5K1C Antibody (VS3-FY1834) in WB.
The PIP5KI gamma expression in mouse brain lysates were detected using the anti-PIP5K1C by western blot assay.
Specifications
- Immunogen
- Recombinant mouse PIP5KI γ protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse Pip5K1C
- Species Reactivity
- Human, Mouse
- Clone
- R06-3J3
- Applications
- Western Blot, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 72 kDa, while the observed molecular weight stands at 90,87 kDa.
- Related Disease
- Lethal Congenital Contracture Syndrome 3 and Lethal Congenital Contracture Syndrome
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Gamma; Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, Gamma; PtdIns(4)P-5-Kinase 1 Gamma; PIP5K1-Gamma; EC 2.7.1.68; Phosphatidylinositol 4-Phosphate 5-Kinase Type-1 Gamma; Phosphatidylinositol 4-Phosphate 5-Kinase Type I Gamma; Diphosphoinositide Kinase
- Gene ID
- 18717
- UniProt ID
- O70161
- Cellular Localization
- Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane
- Post Translation Modifications
- Phosphorylation on Ser-650 negatively regulates binding to TLN2 and is strongly stimulated in mitosis.
Phosphorylation on Tyr-649 is necessary for targeting to focal adhesions.
- Protein Refseq
- XP_011526150.1; XP_011526151.1; XP_016882029.1; XP_047294489.1; XP_047294490.1
- Function
- PtdIns(4,5)P2 can directly act as a second messenger or can be utilized as a precursor to generate other second messengers: inositol 1,4,5-trisphosphate (IP3), diacylglycerol (DAG) or phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3/PIP3) (By similarity).
PIP5K1A-mediated phosphorylation of PtdIns4P is the predominant pathway for PtdIns(4,5)P2 synthesis (By similarity).
Plays a role in endocytosis mediated by clathrin and AP-2 (adaptor protein complex 2).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1605CT | Recombinant Mouse anti-Human PIP5K1C Monoclonal antibody (EML1359) | WB |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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