Rabbit Anti-PLSCR3 Recombinant Antibody (clone R02-1B9) (CAT#: VS3-FY1837)
Clone R02-1B9 is a rabbit recombinant monoclonal antibody that is specific for human PLSCR3. It cross-reacts with mouse, rat. The PLSCR3 antibody is recommended for detection of target protein by western blot analysis of PLSCR3 in rat lung, mouse lung lysates.
Specific Inquiry
WB
Figure 1 Anti-PLSCR3 Antibody (VS3-FY1837) in WB.
The PLSCR3 expression in rat lung, mouse lung lysates were detected using the anti-PLSCR3 by western blot assay.
Specifications
- Immunogen
- Synthetic peptides of human PLSCR3
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat PLSCR3
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R02-1B9
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 32 kDa, while the observed molecular weight stands at 32 kDa.
- Related Disease
- Barth Syndrome
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- phospholipid scramblase 3; PLSCR3
- Gene ID
- 57048
- UniProt ID
- Q9NRY6
- Sequence Similarities
- Belongs to the phospholipid scramblase family.
- Cellular Localization
- Membrane, Mitochondrion, Mitochondrion inner membrane, Nucleus
- Post Translation Modifications
- Phosphorylation at Thr-21 by PKC/PRKCD upon apoptotic stimuli enhances phospholipid scramblase activity. (Q9NRY6-PLS3_HUMAN)
Palmitoylation regulates its localization to the cell membrane or the nucleus; trafficking to the cell membrane is dependent upon palmitoylation whereas in the absence of palmitoylation, localizes to the nucleus. (Q9NRY6-PLS3_HUMAN)
Modification sites at PhosphoSitePlus (Q9NRY6)
Modification sites at neXtProt
- Protein Refseq
- NP_001188505.1; NP_001356336.1; NP_001356349.1; NP_001356350.1; NP_001356351.1
- Function
- Plays an important role in mitochondrial respiratory function, morphology, and apoptotic response.
Mediates the translocation of cardiolipin from the mitochondrial inner membrane to outer membrane enhancing t-Bid induced cytochrome c release and apoptosis.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "PLSCR3"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1281CT | Recombinant Mouse anti-Human PLSCR3 Monoclonal antibody (EML1732) | WB |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2757 | Hi-Affi™ Recombinant Rabbit Anti-PLSCR3 Monoclonal Antibody (DS2757AB) | WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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