Rabbit Anti-PLSCR3 Recombinant Antibody (clone R02-1B9) (CAT#: VS3-FY1837)
Clone R02-1B9 is a rabbit recombinant monoclonal antibody that is specific for human PLSCR3. It cross-reacts with mouse, rat. The PLSCR3 antibody is recommended for detection of target protein by western blot analysis of PLSCR3 in rat lung, mouse lung lysates.
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WB
Figure 1 Anti-PLSCR3 Antibody (VS3-FY1837) in WB.
The PLSCR3 expression in rat lung, mouse lung lysates were detected using the anti-PLSCR3 by western blot assay.
Specifications
- Immunogen
- Synthetic peptides of human PLSCR3
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat PLSCR3
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R02-1B9
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 32 kDa, while the observed molecular weight stands at 32 kDa.
- Related Disease
- Barth Syndrome
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- phospholipid scramblase 3; PLSCR3
- Gene ID
- 57048
- UniProt ID
- Q9NRY6
- Sequence Similarities
- Belongs to the phospholipid scramblase family.
- Cellular Localization
- Membrane, Mitochondrion, Mitochondrion inner membrane, Nucleus
- Post Translation Modifications
- Phosphorylation at Thr-21 by PKC/PRKCD upon apoptotic stimuli enhances phospholipid scramblase activity. (Q9NRY6-PLS3_HUMAN)
Palmitoylation regulates its localization to the cell membrane or the nucleus; trafficking to the cell membrane is dependent upon palmitoylation whereas in the absence of palmitoylation, localizes to the nucleus. (Q9NRY6-PLS3_HUMAN)
Modification sites at PhosphoSitePlus (Q9NRY6)
Modification sites at neXtProt
- Protein Refseq
- NP_001188505.1; NP_001356336.1; NP_001356349.1; NP_001356350.1; NP_001356351.1
- Function
- Plays an important role in mitochondrial respiratory function, morphology, and apoptotic response.
Mediates the translocation of cardiolipin from the mitochondrial inner membrane to outer membrane enhancing t-Bid induced cytochrome c release and apoptosis.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1281CT | Recombinant Mouse anti-Human PLSCR3 Monoclonal antibody (EML1732) | WB |
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