Mouse Anti-PMS2 Recombinant Antibody (clone 5A7F2) (CAT#: VS7-0425-WR642)

• Immunogen
• Recombinant human PMS2 (AA: 748-851) fragment expressed in E. Coli.

• Host Species
• Mouse

• Type
• Mouse IgG2b

• Specificity
• Human PMS2

• Species Reactivity
• Human

• Clone
• 5A7F2

• Molecule Class
• Mutl/Hexb Family

• Applications
• WB, FC

• Conjugate
• Unconjugated

• Related Disease
• Lynch syndrome 4 (LYNCH4); Mismatch repair cancer syndrome 4 (MMRCS4)

• Clonality
• Monoclonal

• Purity
• >95% as determined by SDS-PAGE and SEC-HPLC analysis

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• PBS

• Preservative
• 0.05% sodium azide

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Application Notes
• Western Blot: 1:500 - 1:2000
  Flow Cytometry: 1:200 - 1:400
  Enzyme-linked Immunosorbent Assay: 1:10000

• Alternative Names
• PMS2; Mismatch Repair Endonuclease PMS2; DNA Mismatch Repair Protein PMS2; PMS2CL; PMS1 Protein Homolog 2; Postmeiotic Segregation Increased (S. Cerevisiae) 2; PMSL2; EC 3.1.-.-; HNPCC4

• Gene ID
• 5395

• UniProt ID
• P54278

• Long Name
• Mismatch repair endonuclease PMS2

• Cellular Localization
• Nucleus

• Post Translation Modifications
• Phosphoprotein

• Protein Refseq
• NP_000526.2

• Function
• DNA-binding; Endonuclease; Hydrolase; Nuclease

Isotype Control

• MOB-203CQ
• Mouse IgG2b, kappa Isotype Control Antibody

Secondary Antibody

• 2RD-A1466-YJ
• Goat Anti-Mouse IgG2b Secondary antibody

• 2RD-A1560-YJ
• Rabbit Anti-Mouse IgG2b Secondary antibody (Clone RM108)

Reconstitution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

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