Specifications

Immunogen
Synthetic peptide of human POLR2E

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human, Mouse and Rat POLR2E

Species Reactivity
Human, Mouse, Rat

Clone
R05-8J5

Applications
Western Blot, Immunohistochemistry-Paraffin

MW
The calculated weight of the target protein is approximately 25 kDa, while the observed molecular weight stands at 25 kDa.

Related Disease
Esophageal Cancer

Product Property

Purification
Affinity Purified

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
RPB5; XAP4; RPABC1; hRPB25; hsRPB5

Gene ID
5434

UniProt ID
P19388

Sequence Similarities
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.

Cellular Localization
DNA-directed RNA polymerase, Nucleus

Post Translation Modifications
Ubiquitination at Lys115 (NX_P19388 [NX_P19388-1])
Modification sites at PhosphoSitePlus (P19388)
Glycosylation from GlyGen (P19388) 1 site, 1 O-linked glycan (1 site)

Protein Refseq
XP_011526372.1; XP_016882372.1; XP_054177215.1; XP_054177216.1; NP_001303252.1

Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery.

Recommended Products

Secondary Antibody

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

See other products for "POLR2E"

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Rabbit Monoclonal Antibody Products Non-Human Primate (NHP) Antibody Products

CAT	Product Name	Application	Type
MOR-2784	Hi-Affi™ Recombinant Rabbit Anti-POLR2E Monoclonal Antibody (DS2784AB)	IHC-P, WB, FC	IgG

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