Mouse Anti-POMC Recombinant Antibody (clone 6D2B5) (CAT#: VS7-0425-WR649)
This product is a mouse IgG1 antibody that binds to human POMC. The antibody 6D2B5 recognizes specific amino acid domain of human POMC (AA: 1-150) . It can be used for ICC assay.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IHC staining of human pituitary gland
(Immunohistochemical staining shows high expression in pituitary gland)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/ih_additional_tissue/46135/849_266_200x200.jpg
(Immunohistochemical staining shows high expression in pituitary gland)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/ih_additional_tissue/46135/849_266_200x200.jpg
Figure 2 Liver
(Hepatocytes
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46135/146483_A_8_4.jpg
(Hepatocytes
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46135/146483_A_8_4.jpg
Figure 3 Testis
(Leydig cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46135/146483_A_6_6.jpg
(Leydig cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46135/146483_A_6_6.jpg
Figure 4 RNA cell line category: Cell line enhanced (HMC-1, THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115138-POMC/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115138-POMC/subcellular
Specifications
- Immunogen
- Recombinant human POMC (AA: 1-150) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human POMC
- Species Reactivity
- Human
- Clone
- 6D2B5
- Molecule Class
- Prohormone Polypeptide Precursor
- Applications
- ICC
- Conjugate
- Unconjugated
- Related Disease
- Obesity (OBESITY); Obesity, early-onset, with adrenal insufficiency and red hair (OBAIRH)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- POMC; Corticotropin-Like Intermediary Peptide; Gamma-MSH; ACTH; CLIP; Melanotropin Beta; Melanotropin Gamma; Beta-Endorphin; Beta-LPH; Adrenocorticotropin; MSH; POC; Proopiomelanocortin Preproprotein; Beta-Melanocyte-Stimulating Hormone;
- Gene ID
- 5443
- UniProt ID
- P01189
- Long Name
- Proopiomelanocortin
- Cellular Localization
- Secreted
- Post Translation Modifications
- Acetylation; Amidation; Cleavage on pair of basic residues; Disulfide bond; Glycoprotein; Phosphoprotein
- Protein Refseq
- NP_000930.1
- Function
- Endorphin; Hormone
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "POMC"
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1827z | Recombinant Anti-Human POMC Antibody | ELISA, IF, FuncS | IgG |
| MOB-0258MZ | Recombinant Mouse Anti-Human POMC Antibody (clone 03B4) | IHC | Mouse antibody |
| VS1-YJ4 | Mouse Anti-POMC Recombinant Antibody (clone 57) | ELISA, IHC-P | Mouse IgG1 |
| VS1-YJ5 | Mouse Anti-POMC Recombinant Antibody (clone 57), HRP | IHC-P | Mouse IgG1 |
| VS3-XY3472 | Rabbit Anti-POMC Recombinant Antibody (clone R02-2J8) | WB, IHC-P, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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