AbPlus™ Anti-PON1 Magnetic Beads (VS-0724-YC327)
CAT#: VS-0724-YC327
The AbPlus Anti-PON1 Magnetic Beads (VS-0724-YC327) is an innovative affinity resin which is bound with anti-PON1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PON1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IHC staining of human liver
Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1610/6964_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Not detected
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000005421-PON1/subcellular
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-PON1 specific antibody
- Target
- PON1
- Immunogen
- Synthetic peptide corresponding to the C-terminus of the human PON1.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy.
- Alternative Names
- ESA; PON; MVCD5
- Gene ID
- 5444
- UniProt ID
- P27169
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "PON1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1710z | Mouse Anti-PON1 Recombinant Antibody (clone 22G10) | WB, ELISA, FC, IHC | Mouse IgG1 |
| VS3-XY1276 | Mouse Anti-PON1 Recombinant Antibody (clone 4G8D3) | IHC, ICC | Mouse IgG1 |
| VS3-XY1277 | Mouse Anti-PON1 Recombinant Antibody (clone 3D3) | ELISA, WB, FC, IHC | Mouse IgG1 |
| VS-0923-FY136 | Recombinant Mouse Anti-PON1 Antibody (VS-0923-FY136) | ELISA, WB | Mouse IgG1 |
| VS3-FY1840 | Rabbit Anti-PON1 Recombinant Antibody (clone R07-4I1) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2788 | Hi-Affi™ Recombinant Rabbit Anti-PON1 Monoclonal Antibody (DS2788AB) | IHC-P, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1700 | Anti-PON1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5569 | Anti-Mouse PON1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5568 | Anti-Human PON1 Immunohistochemistry Kit | IHC |
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