Mouse Anti-PPIH Recombinant Antibody (clone 1C6) (CAT#: VS-0625-FY65)

• Immunogen
• A full-length recombinant human PPIH protein (NP_006338) expressed in E. coli.

• Host Species
• Mouse

• Type
• Mouse IgG1

• Species Reactivity
• Human, Mouse, Rat

• Clone
• 1C6

• Applications
• Western Blot

• Related Disease
• Gastric Tubular Adenocarcinoma and Myxosarcoma

• Purification
• Purified with Protein A or G affinity chromatography

• Purity
• >90% as determined by SDS-PAGE

• Molecular Weight
• The predicted antigen size is approximately 19 kDa.

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• PBS, pH 7.3, 1% BSA, 50% glycerol

• Preservative
• 0.02% Sodium azide

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Application Notes
• Western Blot: 1:2000
  Optimal dilutions for assays should be determined by the user.

• Alternative Names
• CYPH; CYP-20; USA-CYP; SnuCyp-20

• Gene ID
• 10465

• UniProt ID
• O43447

• Long Name
• peptidylprolyl isomerase H

• Sequence Similarities
• Belongs to the cyclophilin-type PPIase family. PPIase H subfamily.

• Cellular Localization
• Nucleus speckle {ECO:0000269 PubMed:9570313}
  Cytoplasm

• Post Translation Modifications
• Ubiquitination at Lys61 and Lys101
  Modification sites at PhosphoSitePlus
  Glycosylation from GlyGen 1 site, 1 O-linked glycan

• Protein Refseq
• XP_005270419.1; XP_047286822.1; XP_054189823.1; XP_054189824.1; NP_001317439.1

• Function
• PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:20676357).
  Participates in pre-mRNA splicing.
  May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.
  May act as a chaperone.

Secondary Antibody

• 2ND-047CQ
• Goat Anti-Mouse IgG1 Antibody, R-PE

• 2RD-A1460-YJ
• Goat Anti-Mouse IgG1 Secondary antibody

Isotype Control

• MOB-065CQ
• Mouse IgG1 Isotype Control Antibody

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