AbPlus™ Anti-PPP2CA Magnetic Beads (7A6)
CAT#: VS-0424-XY214
The AbPlus Anti-PPP2CA Magnetic Beads (7A6) is an innovative affinity resin which is bound with anti-PPP2CA specific antibody (7A6). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PPP2CA protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IHC staining of human kidney
Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43236/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43236/103641_B_9_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43236/103641_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43236/103641_A_9_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43236/103641_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43236/103641_A_5_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/43236/103641_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113575-PPP2CA/subcellular
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-PPP2CA specific antibody (7A6)
- Target
- PPP2CA
- Immunogen
- C-terminal peptide of human PPP2CA catalytic subunit
- Target Species
- Human, Mouse, Rat, S.cerevisiae
- Antibody Clone
- 7A6
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
- Alternative Names
- RP-C; PP2Ac; PP2CA; NEDLBA; PP2Calpha; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha protein phosphatase 2, catalytic subunit, alpha isozyme replication protein C
- Gene ID
- 5515
- UniProt ID
- P67775
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "PPP2CA"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC159 | PE-A*02:01/Human Ser/Thr protein phosphatase 2A (SLLPAIVEL) MHC Tetramer | FCM | |
| MHC-LC160 | APC-A*02:01/Human Ser/Thr Protein phosphatase 2A (SLLPAIVEL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2825 | Hi-Affi™ Recombinant Rabbit Anti-PPP2CA Monoclonal Antibody (DS2825AB) | WB, FC, IP, IHC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| ZG-0518U | Rabbit Anti-Phospho-PPP2CA (Y307) Recombinant Antibody (clone 3F11) | ELISA, WB | Rabbit IgG |
| VS1-YJ181 | Mouse Anti-PPP2CA Recombinant Antibody (clone 2G9) | WB, IP | Mouse IgG1 |
| VS1-YJ182 | Mouse Anti-PPP2CA Recombinant Antibody (clone 2G9), HRP | WB, IP | Mouse IgG1 |
| VS1-YJ187 | Mouse Anti-PPP2CA Recombinant Antibody (clone 7A6) | IP, WB | Mouse IgG1 |
| VS1-YJ188 | Mouse Anti-PPP2CA Recombinant Antibody (clone 7A6), HRP | IP, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1723 | Anti-PPP2CA Immunohistochemistry Kit | IHC | |
| VS-0525-XY5629 | Anti-Mouse PPP2CA Immunohistochemistry Kit | IHC | |
| VS-0525-XY5628 | Anti-Human PPP2CA Immunohistochemistry Kit | IHC | |
| VS-0525-XY5630 | Anti-Bovine PPP2CA Immunohistochemistry Kit | IHC |
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