AbPlus™ Anti-PTPN1 Magnetic Beads (VS-0724-YC842)
CAT#: VS-0724-YC842
The AbPlus Anti-PTPN1 Magnetic Beads (VS-0724-YC842) is an innovative affinity resin which is bound with anti-PTPN1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PTPN1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12542/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in germinal center cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/12542/30853_A_9_8_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15217/36057_B_7_5.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15217/36057_A_7_5.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/15217/36057_A_9_8.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196396-PTPN1/subcellular
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-PTPN1 specific antibody
- Target
- PTPN1
- Immunogen
- Recombinant human PSPC1 fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase.
- Alternative Names
- PSP1
- Gene ID
- 55269
- UniProt ID
- Q8WXF1
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "PTPN1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0801CT | Recombinant Mouse anti-Human PTPN1 Monoclonal antibody (208BU700) | ELISA, WB | |
| PABC-544 | Chicken Anti-PTPN1 Recombinant Antibody (PABC-544) | ELISA, Inhib | Chicken IgY |
| ZG-0532U | Rabbit Anti-PTPN1 Recombinant Antibody (clone 1G3) | ELISA, WB, IHC | Rabbit IgG |
| VS3-CJ733 | Rabbit Anti-PTPN1 Recombinant Antibody (VS3-CJ733) | WB, ICC, IF, IHC, FC | Rabbit IgG |
| VS3-WK1984 | Rabbit Anti-PTPN1 (pS352) Recombinant Antibody (clone R04-1F2) | WB, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0455MZ | Chicken Anti-PTPN1 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2928 | Hi-Affi™ Recombinant Rabbit Anti-PTPN1 Monoclonal Antibody (DS2928AB) | FC, ICC, IHC-P, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0374-CN-S(P) | Chicken Anti-PTPN1 Recombinant Antibody; scFv Fragment (HPAB-0374-CN-S(P)) | WB, ELISA, IP | Chicken scFv |
| HPAB-0375-CN-S(P) | Chicken Anti-PTPN1 Recombinant Antibody; scFv Fragment (HPAB-0375-CN-S(P)) | WB, ELISA, IP | Chicken scFv |
| PSBC-544 | Chicken Anti-PTPN1 Recombinant Antibody scFv Fragment (PSBC-544) | ELISA | Chicken scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0374-CN-F(E) | Chicken Anti-PTPN1 Recombinant Antibody; Fab Fragment (HPAB-0374-CN-F(E)) | WB, ELISA, IP | Chicken Fab |
| HPAB-0375-CN-F(E) | Chicken Anti-PTPN1 Recombinant Antibody; Fab Fragment (HPAB-0375-CN-F(E)) | WB, ELISA, IP | Chicken Fab |
| PFBC-544 | Chicken Anti-PTPN1 Recombinant Antibody Fab Fragment (PFBC-544) | ELISA | Chicken Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC420 | Recombinant Anti-PTPN1 Vesicular Antibody, EV Displayed (VS-0425-YC420) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5858 | Anti-PTPN1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5859 | Anti-Rat PTPN1 Immunohistochemistry Kit | IHC |
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