Mouse Anti-PURB Recombinant Antibody (VS3-FY2847)
CAT#: VS3-FY2847
The anti-PURB product is a recombinant mouse monoclonal antibody that has a high affinity for human and mouse PURB protein. The calculated molecular weight of the protein is about 33.2 kDa. The antibody can be utilized for detection of target protein by Western Blot (1/500-1/2000).
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human and Mouse PURB
- Species Reactivity
- Human, Mouse
- Applications
- Western Blot
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 33.2 kDa.
- Related Disease
- Myelodysplastic Syndrome
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Target
- Alternative Names
- Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB
- Gene ID
- 5814
- UniProt ID
- Q96QR8
- Sequence Similarities
- Belongs to the PUR DNA-binding protein family.
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Ubiquitination at Lys240 (NX_Q96QR8 [NX_Q96QR8-1])
Modification sites at PhosphoSitePlus (Q96QR8)
Glycosylation from GlyGen (Q96QR8) 1 site, 1 O-linked glycan (1 site)
- Function
- Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts.
Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element.
Modulates constitutive liver galectin-3 gene transcription by binding to its promoter.
May play a role in the dendritic transport of a subset of mRNAs (By similarity).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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