Rabbit Anti-PWP1 Recombinant Antibody (clone R01-7B5)
CAT#: VS3-FY1863
This is a rabbit recombinant primary antibody that exhibits selective binding to human PWP1. It can be used in western blot assay with a dillution of 1/500-1/1000. The R01-7B5 is recommended for dilution of target protein by western blot (dilution 1/500-1/1000).
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli rim & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38708/565_B9_2_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136045-PWP1/subcellular
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Specifications
- Immunogen
- Synthetic peptide of human PWP1
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human PWP1
- Species Reactivity
- Human
- Clone
- R01-7B5
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 56 kDa, while the observed molecular weight stands at 75 kDa.
- Related Disease
- Porokeratosis
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- NCLB; IEF-SSP-9502
- Gene ID
- 11137
- UniProt ID
- Q13610
- Sequence Similarities
- Belongs to the WD repeat PWP1 family.
- Cellular Localization
- Chromosome, Nucleus
- Post Translation Modifications
- Ubiquitination at Lys376 (NX_Q13610 [NX_Q13610-1])
Modification sites at PhosphoSitePlus (Q13610)
Glycosylation from GlyGen (Q13610) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001304891.1; NP_001304892.1; NP_008993.1
- Function
- Chromatin-associated factor that regulates transcription.
Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription.
Regulates the epigenetic status of rDNA.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "PWP1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0806CT | Recombinant Mouse anti-Human PWP1 Monoclonal antibody (3962D6b) | WB |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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