This product is a recombinant mouse antibody that recognizes PXN. The antibody was purified by affinity chromatography. It can be used in WB, ELISA.
Figure 1 Immunostaining of native paxillin in A549 cells with Cy-5 labeled LD2 and LD4 sABs.
A549 cells were stained with Cy-5 labeled LD2 and LD4 sAB (red) or were left untreated as a control. Arrowheads point to sites where sABs are bound to paxillin present in focal adhesions. Nuclei were counterstained with Hoehst (blue) and actin filaments were stained with Alexa-488 phalloidin (green). Scale bar corresponds to 10μm. Top panel: isolated red channel representing fluorescence signal from Cy-5 labeled sAB only. Bottom panel: three merged channels representing fluorescence signals from nuclear, actin and paxillin staining.
Nocula-Lugowska, M., Lugowski, M., Salgia, R., & Kossiakoff, A. A. (2015). Engineering synthetic antibody inhibitors specific for LD2 or LD4 motifs of paxillin. Journal of molecular biology, 427(15), 2532-2547.
Figure 2 The sABs pull-down paxillin-FAK complexes.
Paxillin was immunoprecipiatated from A549 lung cancer cell lysate with LD2 and LD4 sABs and the pulled down complexes were visualized either by anti-paxillin or anti-FAK antibody.
Nocula-Lugowska, M., Lugowski, M., Salgia, R., & Kossiakoff, A. A. (2015). Engineering synthetic antibody inhibitors specific for LD2 or LD4 motifs of paxillin. Journal of molecular biology, 427(15), 2532-2547.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-314 | Human Anti-PXN Recombinant Antibody (clone CBL14Q) | WB, ELISA, IF, FuncS | Human IgG |
PABL-674 | Human Anti-PXN Recombinant Antibody (clone CBL19Q) | WB, FuncS | Human IgG |
PABL-675 | Human Anti-PXN Recombinant Antibody (clone CBL35Q) | WB, FuncS | Human IgG |
MRO-1178-CN | Recombinant Rabbit Anti-PXN Monoclonal Antibody (CBACN-434) | WB, IF, IHC, IP | Rabbit IgG |
ZG-0537U | Rabbit Anti-Phospho-PXN (Y118) Recombinant Antibody (clone 1F11) | ELISA, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-314 | Human Anti-PXN Recombinant Antibody (clone CBL14Q); scFv Fragment | WB, ELISA, IF, FuncS | Human scFv |
PSBL-668 | Human Anti-PXN Recombinant Antibody (clone CBL19Q); scFv Fragment | WB, FuncS | Human scFv |
PSBL-669 | Human Anti-PXN Recombinant Antibody (clone CBL35Q); scFv Fragment | WB, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-314 | Human Anti-PXN Recombinant Antibody (clone CBL14Q); Fab Fragment | WB, ELISA, IF, FuncS | Human Fab |
PFBL-668 | Human Anti-PXN Recombinant Antibody (clone CBL19Q); Fab Fragment | WB, FuncS | Human Fab |
PFBL-669 | Human Anti-PXN Recombinant Antibody (clone CBL35Q); Fab Fragment | WB, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2947 | Hi-Affi™ Recombinant Rabbit Anti-PXN Monoclonal Antibody (DS2947AB) | FC, ICC, IHC-P, IP, WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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