Mouse Anti-RAB14 Recombinant Antibody (VS3-FY2848)

CAT#: VS3-FY2848

This anti-RAB14 product is a recombinant mouse monoclonal antibody with a high affinity for human RAB14 protein. It cross-reacts with mouse, rat species. The calculated molecular weight of the protein is about 23.9 kDa. The antibody can be utilized for detection of RAB14 by Western Blot (1/500-1/2000).

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human, Mouse and Rat RAB14
  • Species Reactivity
  • Human, Mouse, Rat
  • Applications
  • Western Blot
  • Conjugate
  • Unconjugated, FITC
  • MW
  • The molecular weight of the target protein is approximately 23.9 kDa.

Product Property

  • Clonality
  • Monoclonal Antibody
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/2000

Target

  • Alternative Names
  • RAB14, Member RAS Oncogene Family; BA165P4.3 (Member RAS Oncogene Family); Small GTP Binding Protein RAB14; F Protein-Binding Protein 1; Ras-Related Protein Rab-14; RAB-14; FBP
  • Sequence Similarities
  • Belongs to the small GTPase superfamily. Rab family.
  • Cellular Localization
  • Recycling endosome
    Early endosome membrane
    Lipid-anchor
    Cytoplasmic side
    Golgi apparatus membrane
    Lipid-anchor
    Cytoplasmic side
    Golgi apparatus, trans-Golgi network membrane
    Lipid-anchor
    Cytoplasmic side
    Cytoplasmic vesicle, phagosome
  • Post Translation Modifications
  • Ubiquitination at Lys35, Lys171, and Lys193 (NX_P61106 [NX_P61106-1])
    Modification sites at PhosphoSitePlus (P61106)
    Glycosylation from GlyGen (P61106) 1 site, 1 O-linked glycan (1 site)
  • Function
  • May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity).
    Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

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Secondary Antibody

Isotype Control

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