Mouse Anti-RAB14 Recombinant Antibody (VS3-FY2848) (CAT#: VS3-FY2848)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human, Mouse and Rat RAB14

• Species Reactivity
• Human, Mouse, Rat

• Applications
• Western Blot

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 23.9 kDa.

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/2000

• Alternative Names
• RAB14, Member RAS Oncogene Family; BA165P4.3 (Member RAS Oncogene Family); Small GTP Binding Protein RAB14; F Protein-Binding Protein 1; Ras-Related Protein Rab-14; RAB-14; FBP

• Gene ID
• 51552

• UniProt ID
• P61106

• Sequence Similarities
• Belongs to the small GTPase superfamily. Rab family.

• Cellular Localization
• Recycling endosome
  Early endosome membrane
  Lipid-anchor
  Cytoplasmic side
  Golgi apparatus membrane
  Lipid-anchor
  Cytoplasmic side
  Golgi apparatus, trans-Golgi network membrane
  Lipid-anchor
  Cytoplasmic side
  Cytoplasmic vesicle, phagosome

• Post Translation Modifications
• Ubiquitination at Lys35, Lys171, and Lys193 (NX_P61106 [NX_P61106-1])
  Modification sites at PhosphoSitePlus (P61106)
  Glycosylation from GlyGen (P61106) 1 site, 1 O-linked glycan (1 site)

• Function
• May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity).
  Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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