Anti-REG4 (clone 12E1.3C11) Recombinant Antibody Coupled Liposome (VS-1024-FY150) (CAT#: VS-1024-FY150)

• Potential Clinical Applications
• Colorectal cancer

• Clone
• 12E1.3C11

• Antibody Type
• IgG

• Antibody Host
• Human

• Antibody Reactivity
• Human

• Antibody Description
• This is a recombinant human monoclonal antibody that was meticulously engineered to specifically target REG4, a protein associated with various pathological conditions. By selectively binding to REG4, this antibody holds promise for innovative therapeutic applications, potentially improving treatment outcomes for diseases where REG4 plays a critical role. The development of this targeted therapy exemplifies advances in biopharmaceutical research, paving the way for more personalized and effective medical interventions.

• Storage
• See in the COA

• Storage Shelf Time
• See in the COA

• Target
• REG4

• Introduction
• Reg protein belonging to the family of calcium-dependent lectin superfamily, according to the structure of the encoded proteins, Reg family can be divided into four subtypes, i.e. I, II, III, IV type, they have similar gene structure, contain 5 introns and 6 exons, the TATA box and CCAAT box located at 27 and 100bp encoding 158-175 amino acids in length, ranging from a secreted protein upstream of the transcription start site.

• Alternative Names
• Regenerating Family Member 4; Gastrointestinal Secretory Protein; Regenerating Islet-Derived Family, Member 4; Regenerating Islet-Derived Protein IV; Regenerating Gene Type IV; REG-Like Protein; Reg IV

• Full Name
• Regenerating Family Member 4

• Gene ID
• 83998

• UniProt ID
• Q9BYZ8

• Cellular Localization
• Secreted

• Post Translation Modifications
• Glycosylation at Asn50 ( NX_Q9BYZ8 [NX_Q9BYZ8-1] )
  Modification sites at PhosphoSitePlus ( Q9BYZ8 )
  Glycosylation from GlyGen (Q9BYZ8) 1 site

• Protein Refseq
• NP_001152824.1; NP_001152825.1; NP_114433.1

• Function
• Calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment.
  May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.

• HPAB-0124-LSX
• Human Anti-REG4 Recombinant Antibody (clone 12E1.3C11)

• HPAB-0124-LSX-F(E)
• Human Anti-REG4 Recombinant Antibody (clone 12E1.3C11); Fab Fragment

• HPAB-0124-LSX-S(P)
• Human Anti-REG4 Recombinant Antibody (clone 12E1.3C11); scFv Fragment

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