Recombinant Anti-RLN2 Eliminating Antibody, pH-Sensitive (VS-0625-YC279)
CAT#: VS-0625-YC279
The anti-RLN2 eliminating antibody is an engineered pH-sensitive antibody against human RLN2. RLN2 plays roles in cardiovascular and reproductive systems, initially linked to pregnancy functions. The antibody has a novel RLN2-sweeping activity in vivo, which selectively eliminatesthe soluble RLN2 from plasma. Compared to conventional antibody, the mAb exerted in vivo efficacy by simultaneously engineering both pH-dependent antigen binding, to mimic the pH-dependent receptor-ligand binding of such endocytic receptors, and increased FcRn binding affinity at neutral pH, to mimic the cell-bound form of the receptors.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (Daudi, HEL, T-47d, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000107014-RLN2
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human RLN2
- Species Reactivity
- Human
- Applications
- Antigen-Sweeping In Vivo.
Product Property
- Purification
- Protein A/G purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- PBS only
- Preservative
- None
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "RLN2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2617z | Mouse Anti-RLN2 Recombinant Antibody (clone 40B12) | ELISA, FC | Mouse IgG1 |
| MOB-0445CT | Recombinant Mouse anti-Human RLN2 Monoclonal antibody (gsfe) | ELISA, FC | |
| HPAB-M0197-YC | Mouse Anti-RLN2 Recombinant Antibody (HPAB-M0197-YC) | ELISA, WB, IP | Mouse IgG |
| VS3-FY1272 | Recombinant Rabbit Anti-RLN2 Antibody (clone R05-7A5) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1915CQ | Recombinant Rat Anti-RLN2 Antibody (CBL619) | WB, Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3077 | Hi-Affi™ Recombinant Rabbit Anti-RLN2 Monoclonal Antibody (DS3077AB) | WB, IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0197-YC-S(P) | Mouse Anti-RLN2 Recombinant Antibody scFv Fragment (HPAB-M0197-YC-S(P)) | ELISA, WB, IP | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0197-YC-F(E) | Mouse Anti-RLN2 Recombinant Antibody Fab Fragment (HPAB-M0197-YC-F(E)) | ELISA, WB, IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY225 | AbPlus™ Anti-RLN2 Magnetic Beads (1B11F12) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6143 | Anti-RLN2 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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