Rabbit Anti-RNF14 Recombinant Antibody (clone R01-1H7) (CAT#: VS3-FY2080)
This R01-1H7 recombinant monoclonal antibody exhibits a high affinity for human RNF14. It cross-reacts with mouse, rat. This RNF14 antibody has been rigorously validated and is widely used in western blot analysis of RNF14 in mouse brain, rat brain lysates.
Specific Inquiry
WB
Figure 1 Anti-RNF14 Antibody (VS3-FY2080) in WB.
The RNF14 expression in mouse brain, rat brain lysates were detected using the anti-RNF14 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human RNF14
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat RNF14
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R01-1H7
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 54 kDa, while the observed molecular weight stands at 54 kDa.
- Related Disease
- Cancer
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Ring Finger Protein 14; RING Finger Protein 14; ARA54; HFB30; Androgen Receptor Associated Protein 54; Androgen Receptor-Associated Protein 54
- Gene ID
- 9604
- UniProt ID
- Q9UBS8
- Sequence Similarities
- Belongs to the RBR family. RNF14 subfamily.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- RING-type zinc finger-dependent and UBE2E2-dependent autoubiquitination. (Q9UBS8-RNF14_HUMAN)
Ubiquitination at Lys372 and Lys386 (NX_Q9UBS8 [NX_Q9UBS8-1])
Modification sites at PhosphoSitePlus (Q9UBS8)
Glycosylation from GlyGen (Q9UBS8) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_011536016.1; XP_016865563.1; XP_016865564.1; XP_024302033.1; XP_047273854.1
- Function
- Specifically required to resolve RNA-protein cross-links caused by reactive aldehydes, which trigger translation stress by stalling ribosomes: acts by catalying 'Lys-6'-linked ubiquitination of RNA-protein cross-links, leading to their removal by the ATP-dependent unfoldase VCP and subsequent degradation by the proteasome.
Independently of its function in the response to stalled ribosomes, acts as a regulator of transcription in Wnt signaling via its interaction with TCF transcription factors (TCF7/TCF1, TCF7L1/TCF3 and TCF7L2/TCF4).
May also play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "RNF14"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1295MZ | Recombinant Mouse Anti-Human RNF14 Antibody | WB | Mouse antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3081 | Hi-Affi™ Recombinant Rabbit Anti-RNF14 Monoclonal Antibody (DS3081AB) | WB, FC | IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS3-FY2080. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.