Mouse Anti-RRAS2 Recombinant Antibody (VS3-CJ1085)
CAT#: VS3-CJ1085
This product is a mouse antibody that recognizes human, and mouse RRAS2.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10420/if_selected.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50942/124222_A_7_3.jpg
Normal Tissue
Figure 3 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50942/124222_A_7_4.jpg
Normal Tissue
Figure 4 Pancreas
Exocrine glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50942/124222_A_2_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50942/124222_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50942/124222_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000133818-RRAS2
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Specifications
- Immunogen
- Recombinant protein of human RRAS2
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human, Mouse RRAS2
- Species Reactivity
- Human, Mouse
- Applications
- WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- 0.09% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot (1:4000).
Target
- Alternative Names
- NS12; TC21
- Gene ID
- 22800
- UniProt ID
- P62070
- Sequence Similarities
- Belongs to the small GTPase superfamily. Ras family.
- Cellular Localization
- Cell membrane, Golgi apparatus, Membrane
- Post Translation Modifications
- May be post-translationally modified by both palmitoylation and polyisoprenylation.
Fatty-acylation at Lys-192, Lys-194; lys-196 and Lys-197 is required for localization to the plasma membrane and activity (PubMed:28406396).
Defatty-acylated by SIRT6, affecting its localization to the plasma membrane (PubMed:28406396).
- Protein Refseq
- NP_001096139.1; NP_001170785.1; NP_001170786.1
- Function
- GTP-binding protein with GTPase activity involved in the regulation of MAPK signaling pathway, thereby controlling multiple cellular processes (PubMed:31130282).
Involved in the regulation of MAPK signaling pathway (PubMed:31130282, PubMed:31130285).
Regulation of craniofacial development (PubMed:31130282, PubMed:31130285).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "RRAS2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0821MZ | Recombinant Mouse Anti-Human RRAS2 Antibody | IHC-P | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1970 | Anti-RRAS2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6241 | Anti-Human RRAS2 Immunohistochemistry Kit | IHC |
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