AbPlus™ Anti-Sfn Magnetic Beads (VS-0724-YC524) (CAT#: VS-0724-YC524)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-Sfn specific antibody

• Target
• Sfn

• Immunogen
• Recombinant mouse 14-3-3 sigma/SFN, aa 1-248.

• Target Species
• Mouse

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• Enables phosphoprotein binding activity and protein kinase binding activity. Involved in several processes, including establishment of skin barrier; positive regulation of protein export from nucleus; and regulation of epidermal cell division. Acts upstream of or within keratinocyte differentiation; negative regulation of keratinocyte proliferation; and regulation of cyclin-dependent protein serine/threonine kinase activity. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in transitional cell carcinoma and vulva squamous cell carcinoma.

• Alternative Names
• Er; Mme1; Ywhas; 14-3-3

• Gene ID
• 55948

• UniProt ID
• O70456

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