AbPlus™ Anti-Sfn Magnetic Beads (VS-0724-YC524)
CAT#: VS-0724-YC524
The AbPlus Anti-Sfn Magnetic Beads (VS-0724-YC524) is an innovative affinity resin which is bound with anti-Sfn specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of Sfn protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11105/if_selected.jpg
Normal Tissue
Figure 2 Skin 1
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11105/ihc_selected.jpg
Normal Tissue
Figure 3 Skin
Cells in basal layer Staining: High Intensity: Strong Quantity:>75% Cells in granular layer Staining: High Intensity: Strong Quantity:>75% Cells in spinous layer Staining: High Intensity: Strong Quantity:>75% Langerhans cells Staining: High Intensity: Strong Quantity:>75% Melanocytes Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40552/84840_B_9_1.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, hTCEpi)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000175793-SFN
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-Sfn specific antibody
- Target
- Sfn
- Immunogen
- Recombinant mouse 14-3-3 sigma/SFN, aa 1-248.
- Target Species
- Mouse
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- Enables phosphoprotein binding activity and protein kinase binding activity. Involved in several processes, including establishment of skin barrier; positive regulation of protein export from nucleus; and regulation of epidermal cell division. Acts upstream of or within keratinocyte differentiation; negative regulation of keratinocyte proliferation; and regulation of cyclin-dependent protein serine/threonine kinase activity. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in transitional cell carcinoma and vulva squamous cell carcinoma.
- Alternative Names
- Er; Mme1; Ywhas; 14-3-3
- Gene ID
- 55948
- UniProt ID
- O70456
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SFN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2173MZ | Recombinant Mouse Anti-Human SFN Antibody | ELISA, WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0529MZ | Chicken Anti-SFN Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3241 | Hi-Affi™ Recombinant Rabbit Anti-SFN Monoclonal Antibody (DS3241AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0007-CN | Recombinant Rabbit Anti-SFN Monoclonal Antibody (SD2070) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-CJ877 | Rabbit Anti-SFN Recombinant Antibody (VS3-CJ877) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC546 | AbPlus™ Anti-SFN Magnetic Beads (VS-0724-YC546) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2050 | Anti-SFN Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6524 | Anti-Human SFN Immunohistochemistry Kit | IHC |
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