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    Mouse Anti-SIRT7 Recombinant Antibody (clone 1E2B2) (CAT#: VS7-0425-WR863)

    This product is a mouse IgG1 antibody that binds to human SIRT7. The antibody 1E2B2 recognizes specific amino acid domain of human SIRT7 (AA: 1-105). It can be used for FC assay.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & nuclear speckles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27284/912_E2_2_selected.jpg
    Figure 2 IF staining of human cell line PC-3
    Figure 2 IF staining of human cell line PC-3
    (Immunofluorescent staining of human cell line PC-3 shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/28246/1450_B9_5_selected.jpg
    Figure 3 IHC staining of human esophagus
    Figure 3 IHC staining of human esophagus
    (Immunohistochemical staining of human esophagus shows nucleolar positivity in squamous epithelial cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53669/135259_B_5_1_selected.jpg
    Figure 4 IF staining of human cell line HEK 293
    Figure 4 IF staining of human cell line HEK 293
    (Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm & nuclear speckles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27284/1182_D12_1_red_green.jpg
    Figure 5 IF staining of human cell line U-251 MG
    Figure 5 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & nuclear speckles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27284/911_E2_1_red_green.jpg
    Normal Tissue
    Figure 6 Cerebral cortex
    Figure 6 Cerebral cortex
    (Glial cells
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Nuclear
    Neuronal cells
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53669/135259_B_8_5.jpg
    Figure 7 Esophagus
    Figure 7 Esophagus
    (Squamous epithelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53669/135259_B_6_1.jpg
    Figure 8 Colon
    Figure 8 Colon
    (Glandular cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear
    Peripheral nerve/ganglion
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53669/135259_A_9_3.jpg
    Figure 9 Kidney
    Figure 9 Kidney
    (Cells in tubules
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53669/135259_A_9_5.jpg
    Figure 10 Testis
    Figure 10 Testis
    (Cells in seminiferous ducts
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear
    Leydig cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53669/135259_A_6_6.jpg
    Figure 11 Lymph node
    Figure 11 Lymph node
    (Germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Nuclear)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/53669/135259_A_8_8.jpg
    RNA Expression
    Figure 12 RNA cell line category: Low cell line specificity
    Figure 12 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000187531-SIRT7

    Specifications

    • Immunogen
    • Recombinant human SIRT7 (AA: 1-105) fragment expressed in E. Coli.
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1
    • Specificity
    • Human SIRT7
    • Species Reactivity
    • Human
    • Clone
    • 1E2B2
    • Molecule Class
    • Sirtuin
    • Applications
    • FC
    • Conjugate
    • Unconjugated

    Product Property

    • Clonality
    • Monoclonal
    • Purity
    • >95% as determined by SDS-PAGE and SEC-HPLC analysis
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • 0.05% sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • Western Blot: 1:500 - 1:2000
      Flow Cytometry: 1:200 - 1:400
      Enzyme-linked Immunosorbent Assay: 1:10000

    Target

    • Alternative Names
    • Sirtuin 7; Regulatory Protein SIR2 Homolog 7; SIR2-Like Protein 7; SIR2L7; Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 7 (S. Cerevisiae); Sirtuin (Silent Mating Type Information Regulation 2, S.Cerevisiae, Homolog) 7; Silent Mating Type Information Regulation 2, S.Cerevisiae, Homolog 7
    • Long Name
    • sirtuin 7
    • Cellular Localization
    • Chromosome; Cytoplasm; Nucleus
    • Post Translation Modifications
    • Methylation; Phosphoprotein; Ubl conjugation
    • Function
    • Chromatin regulator; Hydrolase; Repressor; Transferase

    Recommended Products

    Isotype Control

    Secondary Antibody

    Reconstitution Buffer

    Recommended Dilution Buffer

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "SIRT7"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Chicken IgY Antibody Products
    CAT Product Name Application Type
    DrMAB-543 Recombinant Human Anti-Human SIRT7 Antibody, clone D500 IF, ELISA, IP-MS IgG
    VS3-WK108 Mouse Anti-SIRT7 Recombinant Antibody (clone G10-E2) WB, ELISA Mouse IgG1
    VS7-0425-WR862 Mouse Anti-SIRT7 Recombinant Antibody (clone 1E2G10) IHC Mouse IgG1

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