Rabbit Anti-SLC6A5 Recombinant Antibody (clone R08-1A3)

CAT#: VS3-FY1729

The R08-1A3 recombinant monoclonal antibody exhibits high affinity to human SLC6A5. It cross-reacts with rat. Applications Tested: The GlyT2 antibody has been tested by western blot analysis of Glyt2 in Jurkat, C6 lysates.

Tested Data
Figure 1 Anti-SLC6A5 Antibody (VS3-FY1729) in WB.

Specifications

  • Immunogen
  • Synthetic peptide of human Glyt2
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human and Rat SLC6A5
  • Species Reactivity
  • Human, Rat
  • Clone
  • R08-1A3
  • Applications
  • Western Blot
  • MW
  • The calculated weight of the target protein is approximately 87 kDa, while the observed molecular weight stands at 87 kDa.
  • Related Disease
  • Hyperekplexia 3 and Hyperekplexia

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000

Target

  • Alternative Names
  • Solute Carrier Family 6 Member 5; Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 5; GLYT-2; GLYT2; NET1; Solute Carrier Family 6 (Neurotransmitter Transporter), Member 5; Sodium- And Chloride-Dependent Glycine Transporter 2; Glycine Transporter 2; HKPX3
  • Sequence Similarities
  • Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A5 subfamily.
  • Cellular Localization
  • Cell membrane
  • Post Translation Modifications
  • N-glycosylated.
  • Function
  • Sodium- and chloride-dependent glycine transporter.
    Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals.
    May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Secondary Antibody

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