AbPlus™ Anti-SSB Magnetic Beads (VS-0424-XY247) (CAT#: VS-0424-XY247)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-SSB specific antibody

• Target
• SSB

• Target Species
• Human

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.

• Alternative Names
• Sjogren Syndrome Antigen B; La Autoantigen; La Ribonucleoprotein Domain Family, Member 3; Sjoegren Syndrome Type B Antigen; Lupus La Protein; SS-B; Sjogren Syndrome Antigen B (Autoantigen La); La Ribonucleoprotein

• Gene ID
• 6741

• UniProt ID
• P05455

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