AbPlus™ Anti-SSB Magnetic Beads (VS-0724-YC183)
CAT#: VS-0724-YC183
The AbPlus Anti-SSB Magnetic Beads (VS-0724-YC183) is an innovative affinity resin which is bound with anti-SSB specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of SSB protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17287/if_selected.jpg
Subcellular Location
Figure 2 IHC staining of human nasopharynx
Immunohistochemical staining of human nasopharynx shows strong nuclear positivity in respiratory epithelial cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/17287/40060_B_8_2_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Glial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Neuronal cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_8_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Hepatocytes
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_8_4.jpg
Normal Tissue
Figure 6 Pancreas
Exocrine glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Pancreatic endocrine cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_2_3.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Cells in tubules
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_9_5.jpg
Normal Tissue
Figure 8 Testis
Leydig cells
Staining:
High
Intensity: Strong
Quantity:>75%
Pachytene spermatocytes
Staining:
High
Intensity: Strong
Quantity:>75%
Peritubular cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Preleptotene spermatocytes
Staining:
High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining:
High
Intensity: Strong
Quantity:>75%
Sertoli cells
Staining:
High
Intensity: Strong
Quantity:>75%
Spermatogonia cells
Staining:
High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_5_6.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Non-germinal center cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4643/15243_A_8_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000138385-SSB
❮
❯
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-SSB specific antibody
- Target
- SSB
- Immunogen
- Recombinant human SSB fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014]
- Alternative Names
- Sjogren Syndrome Antigen B; La Autoantigen; La Ribonucleoprotein Domain Family, Member 3; Sjoegren Syndrome Type B Antigen; Lupus La Protein; SS-B; Sjogren Syndrome Antigen B (Autoantigen La); La Ribonucleoprotein;
- Gene ID
- 6741
- UniProt ID
- P05455
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
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| HPAB-0883-FY-F(E) | Mouse Anti-SSB Recombinant Antibody; Fab Fragment (HPAB-0883-FY-F(E)) | WB, IP, IF | Mouse Fab |
| CAT | Product Name | Application | Type |
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| FAMAB-0193-YC-F(E) | Mouse Anti-SSB Recombinant Antibody (clone 2); Fab Fragment | ELISA, FuncS | Mouse Fab |
| FAMAB-0194-YC-F(E) | Mouse Anti-SSB Recombinant Antibody (clone 14); Fab Fragment | ELISA, FuncS | Mouse Fab |
| HPAB-0881-FY-S(P) | Mouse Anti-SSB Recombinant Antibody; scFv Fragment (HPAB-0881-FY-S(P)) | WB, IP, IF | Mouse scFv |
| HPAB-0882-FY-S(P) | Mouse Anti-SSB Recombinant Antibody; scFv Fragment (HPAB-0882-FY-S(P)) | WB, IP, IF | Mouse scFv |
| HPAB-0883-FY-S(P) | Mouse Anti-SSB Recombinant Antibody; scFv Fragment (HPAB-0883-FY-S(P)) | WB, IP, IF | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY247 | AbPlus™ Anti-SSB Magnetic Beads (VS-0424-XY247) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6915 | Anti-SSB Immunohistochemistry Kit | IHC | |
| VS-0525-XY6916 | Anti-Human SSB Immunohistochemistry Kit | IHC |
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