Rabbit Anti-SST Recombinant Antibody (clone R28-4V-8) (CAT#: VS3-XY3514)
It is a recombinant rabbit antibody specific for SST (Somatostatin), which impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH. This antibody specifically targets human, mouse and rat SST. This product has been tested using Immunohistochemistry-Paraffin. The recommended dilutions of Immunohistochemistry-Paraffin is 1/50-1/100.
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Normal Tissue
RNA Expression
Figure 1 Duodenum
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19472/164703_A_8_2_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19472/164703_A_8_2_val_selected.jpg
Figure 2 Cerebral cortex
(Neuropil Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19472/164703_B_9_5.jpg
(Neuropil Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19472/164703_B_9_5.jpg
Figure 3 Colon
(Endocrine cells Staining: High Intensity: Strong Enterocytes -)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19472/164703_A_7_3.jpg
(Endocrine cells Staining: High Intensity: Strong Enterocytes -)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19472/164703_A_7_3.jpg
Figure 4 RNA cell line category: Cell line enhanced (EFO-21, U-2 OS, U-251 MG, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157005-SST
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157005-SST
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat SST
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R28-4V-8
- Applications
- IHC-P
- Related Disease
- Somatostatinoma; Islet Cell Tumor
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- IHC: 1/100-1/200
Target
- Alternative Names
- SMST; SST1
- Gene ID
- 6750
- UniProt ID
- P61278
- Long Name
- Somatostatin
- Sequence Similarities
- Belongs to the somatostatin family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- C-terminal amidation of the neuronostatin peptide is required for its biological activity, including for the regulation of mean arterial pressure.
- Protein Refseq
- NP_001039.1
- Function
- Somatostatin-14:
Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH; the inhibition of ghrelin-stimulated secretion of GH1 can be further increased by neuronostatin.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibodies
IgG Antibodies
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3413 | Hi-Affi™ Recombinant Rabbit Anti-SST Monoclonal Antibody (DS3413AB) | IHC-P | IgG |
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For Research Use Only. Not For Clinical Use.
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