Rabbit Anti-SST Recombinant Antibody (clone R28-4V-8)

CAT#: VS3-XY3514

It is a recombinant rabbit antibody specific for SST (Somatostatin), which impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH. This antibody specifically targets human, mouse and rat SST. This product has been tested using Immunohistochemistry-Paraffin. The recommended dilutions of Immunohistochemistry-Paraffin is 1/50-1/100.

Gene Expression
Figure 1 Duodenum Figure 2 Cerebral cortex Figure 3 Colon Figure 4 RNA cell line category: Cell line enhanced (EFO-21, U-2 OS, U-251 MG, U-698)

Specifications

  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat SST
  • Species Reactivity
  • Human, Mouse, Rat
  • Clone
  • R28-4V-8
  • Applications
  • IHC-P
  • Related Disease
  • Somatostatinoma; Islet Cell Tumor

Product Property

  • Clonality
  • Monoclonal
  • Aggregation
  • < 5%
  • Format
  • Liquid
  • Buffer
  • PBS (pH 7.4), 150 mM NaCl and 50% glycerol
  • Preservative
  • 0.02% sodium azide
  • Storage
  • Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shipping
  • Ice packs

Applications

  • Application Notes
  • IHC: 1/100-1/200

Target

  • Alternative Names
  • SMST; SST1
  • Long Name
  • Somatostatin
  • Sequence Similarities
  • Belongs to the somatostatin family.
  • Cellular Localization
  • Secreted
  • Post Translation Modifications
  • C-terminal amidation of the neuronostatin peptide is required for its biological activity, including for the regulation of mean arterial pressure.
  • Function
  • Somatostatin-14:
    Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH; the inhibition of ghrelin-stimulated secretion of GH1 can be further increased by neuronostatin.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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