Mouse Anti-Suz12 Recombinant Antibody (clone 0725W49)
CAT#: VS-0725-FY215
The Mouse Anti-Suz12 Recombinant Antibody (clone 0725W49) is a recombinant antibody developed against full-length human Suz12. It is suitable for Chromatin Immunoprecipitation (ChIP) and Western Blot (WB). Suz12 is a zinc finger gene found at breakpoints of chromosomal translocations in endometrial stromal sarcoma, playing a role as a Polycomb protein involved in transcriptional repression. This antibody is a valuable tool for studying epigenetic mechanisms and cancer research.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoli & nuclear bodies.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/1043_A4_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human appendix
Immunohistochemical staining of human appendix shows nuclear positivity in lymphoid tissue and glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_1_2_selected.jpg
Normal Tissue
Figure 3 Colon
Glandular cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_7_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_7_5.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_9_8.jpg
RNA Expression
Figure 6 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000178691-SUZ12/subcellular
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Specifications
- Immunogen
- A recombinant protein corresponding to full-length human Suz12.
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human Suz12
- Species Reactivity
- Human
- Clone
- 0725W49
- Applications
- Chromatin Immunoprecipitation, Western Blot
- Related Disease
- Cancer
Product Property
- Purification
- Protein G purified
- Molecular Weight
- The molecular weight of the antigen is 95 kDa.
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol
- Preservative
- 0.035% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Chromatin Immunoprecipitation: 2.5-10 µg per Chromatin Immunoprecipitation
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "SUZ12"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1974MZ | Recombinant Mouse Anti-Human SUZ12 Antibody | ELISA, IHC-P, WB | Mouse antibody |
| VS3-QX1078 | Mouse Anti-SUZ12 Recombinant Antibody (clone 2B12-B4-C0) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-WK973 | Rabbit Anti-SUZ12 Recombinant Antibody (VS3-WK973) | WB, ICC, IF, IP | Rabbit IgG |
| VS3-FY1416 | Recombinant Rabbit Anti-SUZ12 Antibody (clone R07-6C3) | WB, IP | Rabbit IgG |
| VS7-0425-WR933 | Mouse Anti-SUZ12 Recombinant Antibody (clone 2B9G12) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3472 | Hi-Affi™ Recombinant Rabbit Anti-SUZ12 Monoclonal Antibody (DS3472AB) | WB, ICC, IF, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY497 | Rabbit Anti-NHP SUZ12 Recombinant Antibody (VS-1024-XY497) | WB, IF, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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